Recombinant Human CCL14, His-tagged

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Recombinant Human CCL14, His-tagged

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Cat. No. : CCL14-167H
Product Overview : Recombinant human CCL14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Description : CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1α. It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1(9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5.
Source : E.coli.
Form : Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol.
Molecular Weight : 10.9 kDa (95aa) confirmed by MALDI-TOF.
Purity : > 95% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Endotoxin Level : < 1.0 EU per 1 μg of protein (determined by LAL method).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MTKTESSSRG PYHPSECCFT YTTYKIPRQR IMDYYETNSQ CSKPGIVFIT KRGHSVCTNP SDKWVQDYIK DMKEN.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Cytokine-cytokine receptor interaction
Gene Name : CCL14 chemokine (C-C motif) ligand 14 [ Homo sapiens ]
Synonyms : OTTHUMP00000176860; SCYA14; SY14; SCYL2; NCC-2; NCC2; CKb1; MCIF; CC-1; CC-3; CCL14; HCC-1; HCC-1(1-74); HCC-1/HCC-3; chemokine (C-C motif) ligand 14; chemokine CC-1; HCC-3; chemokine CC-3; Chemokine CC-1/CC-3; FLJ16015; Small-inducible cytokine A14; small inducible cytokine subfamily A (Cys-Cys), member 14
Gene ID : 6358
mRNA Refseq : NM_032963
Protein Refseq : NP_116739
MIM : 601392
UniProt ID : Q16627
Chromosome Location : 17q11.2
Function : chemokine activity; protein binding; signal transducer activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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