"CCL14" Related Products

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Recombinant Human CCL14, His-tagged

Cat. No.: CCL14-167H
Product Overview: Recombinant human CCL14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Description: CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1α. It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1(9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5.
Source: E.coli.
Form: Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol.
Molecular Weight: 10.9 kDa (95aa) confirmed by MALDI-TOF.
Purity: > 95% by SDS - PAGE.
Concentration: 0.5 mg/ml (determined by Bradford assay).
Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MTKTESSSRG PYHPSECCFT YTTYKIPRQR IMDYYETNSQ CSKPGIVFIT KRGHSVCTNP SDKWVQDYIK DMKEN.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Cytokine-cytokine receptor interaction
Gene Name: CCL14 chemokine (C-C motif) ligand 14 [ Homo sapiens ]
Synonyms: OTTHUMP00000176860; SCYA14; SY14; SCYL2; NCC-2; NCC2; CKb1; MCIF; CC-1; CC-3; CCL14; HCC-1; HCC-1(1-74); HCC-1/HCC-3; chemokine (C-C motif) ligand 14; chemokine CC-1; HCC-3; chemokine CC-3; Chemokine CC-1/CC-3; FLJ16015; Small-inducible cytokine A14; small inducible cytokine subfamily A (Cys-Cys), member 14
Gene ID: 6358
mRNA Refseq: NM_032963
Protein Refseq: NP_116739
MIM: 601392
UniProt ID: Q16627
Chromosome Location: 17q11.2
Function: chemokine activity; protein binding; signal transducer activity

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