Recombinant Human MESDC2, His-tagged

• Cat.No.: MESDC2-3403H
• Product Overview: Recombinant human MESDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Cat. No.: MESDC2-3403H
• Description: MESDC2, also known as Mesoderm development candidate 2, is required for formation of the primitive streak and mesoderm during embryogenesis. This protein binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression.
• Source: E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT.
• Molecular Weight: 24.9 kDa (222aa) confirmed by MALDI-TOF.
• Purity: > 90% by SDS - PAGE.
• Concentration: 1.0 mg/ml (determined by BCA assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MAEGSPGTPD ESTPPPRKKK KDIRDYNDAD MA R LLEQWEK DDDIEEGDLP EHKRPSAPVD FSKIDPSKPESILKMTKKGK TLM MF VTVSG SPTEKETEEI TSLWQGSLFN ANYDVQRFIV GSDRAIFMLR DGSYAWEIKD FLVGQDRCAD VTLEGQVYPG KGGGSKEKNK TKQDKGKKKK EGDLKSRSSK EENRAGNKRE DL.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: MESDC2 mesoderm development candidate 2 [ Homo sapiens ]
• Synonyms: mesoderm development candidate 2;BOCA; MESD; KIAA0081; MESDC2; LDLR chaperone MESD; mesoderm development protein; renal carcinoma antigen NY-REN-61; Mesoderm development protein; Renal carcinoma antigen NY-REN-61
• Gene ID: 23184
• mRNA Refseq: NM_015154
• Protein Refseq: NP_055969
• MIM: 607783
• UniProt ID: Q14696
• Chromosome Location: 15q13
• Function: molecular_function