Recombinant Human DCUN1D1 protein, His-tagged

• Cat.No.: DCUN1D1-3430H
• Product Overview: Recombinant Human DCUN1D1(1-259aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: DCuN1D1, also known as DCN1-like protein 1, is involved in the malignant transformation of squamous cell lineage. This protein regulates Gli1, a key regulator of the hedgehog (HH) pathway that plays an important role in development, maintenance, and regeneration of almost all adult tissues.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
• Molecular Mass: 32.2 kDa (279aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSHRYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL DRKKLEQLYNTFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI DDFVEFARPQIAGTKSTTV
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DCUN1D1
• Synonyms: DCUN1D1; DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae); DCN1-like protein 1; DCUN1L1; RP42; SCCRO; SCRO; Tes3; RP42 homolog; DCUN1 domain-containing protein 1; squamous cell carcinoma-related oncogene; defective in cullin neddylation protein 1-like protein 1; DCNL1
• Gene ID: 54165
• mRNA Refseq: NM_020640
• Protein Refseq: NP_065691
• MIM: 605905
• UniProt ID: Q96GG9
• Chromosome Location: 3q26.3
• Function: protein binding