"TAGLN2" Related Products

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Recombinant Human TAGLN2, His-tagged

Cat. No.: TAGLN2-3447H
Product Overview: Recombinant human TAGLN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description: TAGLN2, also known transgelin 2, is one of the earliest markers of differentiated smooth muscle. This protein contains a calponin like repeat and a calponin-homology (CH) domain. It is downregulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. It also binds actin, causing actin fibers to gel within minutes of binding. Binding of transgelin to actin occurs at a ratio of 1:6 actin monomers.
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Molecular Weight: 23.4 kDa (208aa), confirmed by MALDI-TOF
Purity: > 90% by SDS - PAGE
Concentration: 1.0 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MEVQQKIEKQ YDADLEQILI QWITTQCRKD VGRPQPGREN FQNWLKDGTV LCELINALYP EGQAPVKKIQ ASTMAFKQME QISQFLQAAE RYGINTTDIF QTVDLWEGKN MACVQRTLMN LGGLAVARDD GLFSGDPNWF PKKSKENPRN FSDNQLQEGK NVIGLQMGTN RGASQAGMTG YGMPRQIL
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: TAGLN2 transgelin 2 [ Homo sapiens ]
Synonyms: TAGLN2; HA1756; KIAA0120; SM22-alpha homolog; OTTHUMP00000024408; OTTHUMP00000024410; transgelin-2
Gene ID: 8407
mRNA Refseq: NM_003564
Protein Refseq: NP_003555
MIM: 604634
UniProt ID: protein binding
Chromosome Location: 1q21-q25
Function: protein binding

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