| Cat. No.: | PDAP1-2770H |
| Product Overview: | Recombinant human PDAP1 protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.MW = 21.7kDa (189aa). |
| Description: | PDGFA associated protein 1, also known as PDAP1, enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. And its expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha. |
| Source: | E.coli. |
| Form: | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF. |
| Purity: | > 90% by SDS - PAGE. |
| Concentration: | 1 mg/ml (determined by Bradford assay). |
| Sequences Of Amino Acids: | MPKGGRKGGH KGRARQYTSP EEIDAQLQAE KQKAREEEEQ KEGGDGAAGD PK K EKK SLDS DESEDEEDDY QQKRKGVEGL IDIENPNRVA QTTKKVTQLD LDGP KELSRR EREEIEKQKA KERYMKMHLA GKTEQAKADL ARLAIIRKQR EEAA RKKEEE RKAKDDATLS GKRMQSLSLN KLEHHHHHH. |
| Storage: | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Gene Name: | PDAP1 PDGFA associated protein 1 [ Homo sapiens ] |
| Synonyms: | PDGFA associated protein 1; PAP; PAP1; HASPP28; PDAP1; 28 kDa heat- and acid-stable phosphoprotein; PDGF associated protein; PDGF-associated protein; PDGFA-associated protein 1 |
| Gene ID: | 11333 |
| mRNA Refseq: | NM_014891 |
| Protein Refseq: | NP_055706 |
| MIM: | 607075 |
| UniProt ID: | Q13442 |
| Chromosome Location: | 7q22.1 |
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