| Cat. No. : | PDAP1-2770H |
| Product Overview : | Recombinant human PDAP1 protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.MW = 21.7kDa (189aa). |
| Description : | PDGFA associated protein 1, also known as PDAP1, enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. And its expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha. |
| Source : | E.coli. |
| Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF. |
| Purity : | > 90% by SDS - PAGE. |
| Concentration : | 1 mg/ml (determined by Bradford assay). |
| Sequences Of Amino Acids : | MPKGGRKGGH KGRARQYTSP EEIDAQLQAE KQKAREEEEQ KEGGDGAAGD PK K EKK SLDS DESEDEEDDY QQKRKGVEGL IDIENPNRVA QTTKKVTQLD LDGP KELSRR EREEIEKQKA KERYMKMHLA GKTEQAKADL ARLAIIRKQR EEAA RKKEEE RKAKDDATLS GKRMQSLSLN KLEHHHHHH. |
| Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Gene Name : | PDAP1 PDGFA associated protein 1 [ Homo sapiens ] |
| Synonyms : | PDGFA associated protein 1; PAP; PAP1; HASPP28; PDAP1; 28 kDa heat- and acid-stable phosphoprotein; PDGF associated protein; PDGF-associated protein; PDGFA-associated protein 1 |
| Gene ID : | 11333 |
| mRNA Refseq : | NM_014891 |
| Protein Refseq : | NP_055706 |
| MIM : | 607075 |
| UniProt ID : | Q13442 |
| Chromosome Location : | 7q22.1 |
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