Recombinant Human DR1, His-tagged DR1-2777H

Recombinant Human DR1, His-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human DR1, His-tagged

Recombinant Human DR1, His-tagged

DR1 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : DR1-2777H
Product Overview : Recombinant human DR1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography.MW = 21.6 kDa(196aa).
Description : DR1, also known as NC2-beta, is a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 may shift the physiological balance of transcriptional output in favor of polymerase I.
Source : E.coli.
Form : Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 0.1 mM PMSF ,10% Glycerol.
Purity : > 85% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MASSSGNDDD LTIPRAAINK MIKETLPNVR VAND ARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEHVIQALESLGF GSYISEVKEV LQE CKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WL QMQQAAQQ AQLAAASASA SNQAGSSQDE EDDDDI.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) [ Homo sapiens ]
Synonyms : DR1; down-regulator of transcription 1, TBP-binding (negative cofactor 2); NC2; NC2-BETA; down-regulator of transcription 1; OTTHUMP00000012557; Protein Dr1; TATA-binding protein-associated phosphoprotein; Negative cofactor 2-beta; NC2-beta
Gene ID : 1810
mRNA Refseq : NM_001938
Protein Refseq : NP_001929
MIM : 601482
UniProt ID : Q01658
Chromosome Location : 1p22.1
Function : sequence-specific DNA binding; transcription corepressor activity; transcription factor binding

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy