"LIF" Related Products

Expand
Expand

Recombinant Human LIF, His-GST

Cat. No.: LIF-472H
Product Overview: Recombinant human LIF protein, fused to His GST-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 47.2 kDa (415aa) confirmed by MALDI-TOF.
Description: Leukemia inhibitory factor, also known as LIF, is a pleiotropic cytokine that is expressed by a wide variety of cells including activated T lymphocytes, monocytes, mast cells and neuronal cells. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.
Source: E.coli.
Sequences Of Amino Acids: MHHHHHHMSP ILGYWKIKGL VQPTRLLLEY LEEKYEEHLY ERDEGDKWRN KKFELGLEFP NLPYYIDGDV KLTQSMAIIR YIADKHNMLG GCPKERAEIS MLEGAVLDIR YGVSRIAYSK DFETLKVDFL SKLPEMLKMF EDRLCHKTYL NGDHVTHPDF MLYDALDVVL YMDPMCLDAF PKLVCFKKRI EAIPQIDKYL KSSKYIAWPL QGWQATFGGG DHPPKSDLVP RGSHMSPLPI TPVNATCAIR HPCHNNLMNQ IRSQLAQLNG SANALFILYY TAQGEPFPNN LDKLCGPNVT DFPPFHANGT EKAKLVELYR IVVYLGTSLG NITRDQKILN PSALSLHSKL NATADILRGL LSNVLCRLCS KYHVGHVDVT YGPDTSGKDV FQKKKLGCQL LGKYKQIIAV LAQAF
Purity: > 90% by SDS – PAGE.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 50mM NaCl.
Concentration: 1 mg/ml (determined by Bradford assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: LIF leukemia inhibitory factor (cholinergic differentiation factor) [ Homo sapiens ]
Synonyms: LIF; leukemia inhibitory factor (cholinergic differentiation factor);CDF; D-FACTOR; Emfilermin; HILDA; MLPLI; D factor; Differentiation- stimulating factor; Leukemia inhibitory factor precursor; Melanoma-derived LPL inhibitor; Cholinergic differentiation factor
Gene ID: 3976
mRNA Refseq: NM_002309
Protein Refseq: NP_002300
MIM: 159540
UniProt ID: P15018
Chromosome Location: 22q12.2
Pathway: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Function: Cytokine activity, Growth factor activity, Leukemia inhibitory factor receptor binding, Oncostatin-M receptor binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.