"MAGEA3" Related Products

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Recombinant Human Melanoma Antigen Family A, 3, His-tagged

Cat. No.: MAGEA3-2837H
Product Overview: Recombinant human MAGEA3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 37.1 kDa (337aa) confirmed by MALDI-TOF.
Description: Melanoma-associated antigen 3, also known MAGEA3, is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGEA3 is a tumor-specific antigen widely expressed in solid and hematologic malignancies, but not in normal tissues, with the exception of testis and placenta. Therefore, MAGEA3 is an excellent candidate tumor antigen.
Source: E.coli.
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MGSMPLEQRS QHCKPEEGLE ARGEALGLVG AQAPATEEQE AASSSSTLVE VTLGEVPAAE SPDPPQSPQG ASSLPTTMNY PLWSQSYEDS SNQEEEGPST FPDLESEFQA ALSRKVAELV HFLLLKYRAR EPVTKAEMLG SVVGNWQYFF PVIFSKASSS LQLVFGIELM EVDPIGHLYI FATCLGLSYD GLLGDNQIMP KAGLLIIVLA IIAREGDCAP EEKIWEELSV LEVFEGREDS ILGDPKKLLT QHFVQENYLE YRQVPGSDPA CYEFLWGPRA LVETSYVKVL HHMVKISGGP HISYPPLHEW VLREGEE
Purity: > 90% by SDS – PAGE.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl.
Concentration: 1 mg/ml (determined by Bradford assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: MAGEA3 melanoma antigen family A, 3 [ Homo sapiens ]
Synonyms: MAGEA3; melanoma antigen family A, 3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6; MGC14613; melanoma-associated antigen 3; antigen MZ2-D; MAGE-3 antigen; OTTHUMP00000024221; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3
Gene ID: 4102
mRNA Refseq: NM_005362
Protein Refseq: NP_005353
MIM: 300174
UniProt ID: P43357
Chromosome Location: Xq28

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