Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

Recombinant Human GAS6 full-length, GST-tagged

Cat.No. : GAS6-288TH
Product Overview : Recombinant Human GAS6 full-length, GST-tagged (1 a.a. - 678 a.a) produced in wheat germ expression system contains GST-tag at N-terminal and is purified by proprietary chromatographic techniques.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : GAS6-288TH
Description : This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Sequence of amino acids : MAPSLSPGPAALRRAPQLLLLLLAA ECALAALLP AREATQFLRPRQRRAF QVFEEAKQGHLERECVEELCSREEA REVFENDPETDYFYPRYLDCINKY GSPYTKNSGFATCVQNLPDQCTPNP CDRKGTQACQDLMGNFFCLCKAG WGGRLCDKDVNECSQENGGCLQICH NKPGSFHCSCHSGFELSSDGRT CQDIDECADSEACGEARCKNLPGSY SCLCDEGFAYSSQEKACRDVDEC LQGRCEQVCVNSPGSYTCHCDGRGG LKLSQDMDTCEDILPCVPFSVAK SVKSLYLGRMFSGTPVIRLRFKRLQ PTRLVAEFDFRTFDPEGILLFAGGH Q DSTWIVLALRAGRLELQLRYNGVGR VTSSGPVINHGMWQTISVEELARNL VIKVNRDAVMKIAVAGDLFQPERGL YHLNLTVGGIPFHEKDLVQPINPRL D GCMRSWNWLNGEDTTIQETVKVNTR MQCFSVTERGSFYPGSGFAFYSLD YMRTPLDVGTESTWEVEVVAHIRPA ADTGVLFALWAPDLRAVPLSVALVD Y HSTKKLKKQLVVLAVEHTALALMEI KVCDGQEHVVTVSLRDGEATLEVDG T RGQSEVSAAQLQERLAVLERHLRSP VLTFAGGLPDVPVTSAPVTAFYRGC MTLEVNRRLLDLDEAAYKHSDITAH SCPPVEPAAA
Molecular Weight : 101.3 kDa
Source : Wheat germ
Purification : Glutathione Sepharose 4 Fast Flow
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Storage buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Gene Name : GAS6 growth arrest-specific 6 [ Homo sapiens ]
Official Symbol : GAS6
Synonyms : GAS6; growth arrest-specific 6; AXLLG; growth arrest-specific protein 6; AXL stimulatory factor; AXSF; DKFZp666G247; FLJ34709
Gene ID : 2621
mRNA Refseq : NM_000820
Protein Refseq : NP_000811
MIM : 600441
UniProt ID : Q14393
Chromosome Location : 13q34
Pathway : Cell surface interactions at the vascular wall, organism-specific biosystem; Gamma-carboxylation of protein precursors, organism-specific biosystem; Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystem; Hemostasis, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem
Function : calcium ion binding; receptor agonist activity; receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
How are GAS6 protein expression levels associated with cardiovascular disease? 02/28/2022

Expression level of GAS6 protein is associated with the occurrence and progression of cardiovascular disease. For example, in atherosclerotic lesions, the expression level of GAS6 protein can change and may promote the development of the lesion. In addition, GAS6 protein can also be used as one of the biomarkers of cardiovascular disease prognosis.

How does GAS6 protein relate to other biomarkers? 12/13/2021

The protein has some association with other biomarkers. For example, in breast cancer, the expression level of GAS6 protein can be used to assess the prognosis and treatment effect of breast cancer together with biomarkers such as ERBB2 and EGFR.

What is the role of GAS6 protein in tumor treatment? 01/24/2020

GAS6 protein has a role in tumor treatment. For example, by regulating the expression level of GAS6 protein, tumor cells can be enhanced to radiotherapy or chemotherapy. In addition, GAS6 protein can also be used as a target for targeted therapies such as antibody-drug conjugates.

What is the role of GAS6 protein in the treatment of cardiovascular disease? 11/20/2019

Regulating the expression level of GAS6 protein can influence the development of cardiovascular disease and the treatment effect. For example, certain drugs can inhibit the development of atherosclerotic lesions by inhibiting the expression level of the GAS6 protein. furthermore

How to use the expression level of GAS6 protein for tumor diagnosis and prognosis assessment? 11/02/2019

It can be used to aid in tumor diagnosis and prognosis by measuring the expression level of GAS6 protein. For example, a low-expression GAS6 protein may predict a worse prognosis and greater tumor aggressiveness.

How is GAS6 protein expression related to tumors? 05/16/2019

Expression level of GAS6 protein is related to tumor genesis, development and prognosis. For example, in patients with non-small cell lung cancer, low expression of the GAS6 protein was associated with poorer survival and higher metastasis rates. In addition, GAS6 protein can also serve as a biomarker to predict tumor response to specific treatments.

Customer Reviews (3)

Write a review
Reviews
12/17/2022

    GAS6 is a treasure in the field of scientific research due to its high catalytic efficiency, high safety and high expression level.

    08/16/2022

      The short half-life and high clearance of GAS6 make its action more rapid and transient, allowing for a rapid therapeutic effect.

      07/06/2021

        Green production process of GAS6 is very advanced and uses the most environmentally friendly production process and is very environmentally friendly.

        Ask a Question for All GAS6 Products

        Required fields are marked with *

        My Review for All GAS6 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends