Recombinant Human GAS6 full-length, GST-tagged
Cat.No. : | GAS6-288TH |
Product Overview : | Recombinant Human GAS6 full-length, GST-tagged (1 a.a. - 678 a.a) produced in wheat germ expression system contains GST-tag at N-terminal and is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | GAS6-288TH |
Description : | This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
Sequence of amino acids : | MAPSLSPGPAALRRAPQLLLLLLAA ECALAALLP AREATQFLRPRQRRAF QVFEEAKQGHLERECVEELCSREEA REVFENDPETDYFYPRYLDCINKY GSPYTKNSGFATCVQNLPDQCTPNP CDRKGTQACQDLMGNFFCLCKAG WGGRLCDKDVNECSQENGGCLQICH NKPGSFHCSCHSGFELSSDGRT CQDIDECADSEACGEARCKNLPGSY SCLCDEGFAYSSQEKACRDVDEC LQGRCEQVCVNSPGSYTCHCDGRGG LKLSQDMDTCEDILPCVPFSVAK SVKSLYLGRMFSGTPVIRLRFKRLQ PTRLVAEFDFRTFDPEGILLFAGGH Q DSTWIVLALRAGRLELQLRYNGVGR VTSSGPVINHGMWQTISVEELARNL VIKVNRDAVMKIAVAGDLFQPERGL YHLNLTVGGIPFHEKDLVQPINPRL D GCMRSWNWLNGEDTTIQETVKVNTR MQCFSVTERGSFYPGSGFAFYSLD YMRTPLDVGTESTWEVEVVAHIRPA ADTGVLFALWAPDLRAVPLSVALVD Y HSTKKLKKQLVVLAVEHTALALMEI KVCDGQEHVVTVSLRDGEATLEVDG T RGQSEVSAAQLQERLAVLERHLRSP VLTFAGGLPDVPVTSAPVTAFYRGC MTLEVNRRLLDLDEAAYKHSDITAH SCPPVEPAAA |
Molecular Weight : | 101.3 kDa |
Source : | Wheat germ |
Purification : | Glutathione Sepharose 4 Fast Flow |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | GAS6 growth arrest-specific 6 [ Homo sapiens ] |
Official Symbol : | GAS6 |
Synonyms : | GAS6; growth arrest-specific 6; AXLLG; growth arrest-specific protein 6; AXL stimulatory factor; AXSF; DKFZp666G247; FLJ34709 |
Gene ID : | 2621 |
mRNA Refseq : | NM_000820 |
Protein Refseq : | NP_000811 |
MIM : | 600441 |
UniProt ID : | Q14393 |
Chromosome Location : | 13q34 |
Pathway : | Cell surface interactions at the vascular wall, organism-specific biosystem; Gamma-carboxylation of protein precursors, organism-specific biosystem; Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystem; Hemostasis, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem |
Function : | calcium ion binding; receptor agonist activity; receptor binding |
Products Types
◆ Recombinant Protein | ||
GAS6-898M | Recombinant Mouse GAS6 Protein (Met1-Pro674), His-tagged | +Inquiry |
Gas6-3478M | Recombinant Mouse Gas6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gas6-1563R | Recombinant Rat Gas6 Protein, His&GST-tagged | +Inquiry |
GAS6-3014H | Recombinant Human GAS6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gas6-196M | Recombinant Mouse Gas6 Protein, His/GST-tagged | +Inquiry |
◆ Lysates | ||
GAS6-6017HCL | Recombinant Human GAS6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionExpression level of GAS6 protein is associated with the occurrence and progression of cardiovascular disease. For example, in atherosclerotic lesions, the expression level of GAS6 protein can change and may promote the development of the lesion. In addition, GAS6 protein can also be used as one of the biomarkers of cardiovascular disease prognosis.
The protein has some association with other biomarkers. For example, in breast cancer, the expression level of GAS6 protein can be used to assess the prognosis and treatment effect of breast cancer together with biomarkers such as ERBB2 and EGFR.
GAS6 protein has a role in tumor treatment. For example, by regulating the expression level of GAS6 protein, tumor cells can be enhanced to radiotherapy or chemotherapy. In addition, GAS6 protein can also be used as a target for targeted therapies such as antibody-drug conjugates.
Regulating the expression level of GAS6 protein can influence the development of cardiovascular disease and the treatment effect. For example, certain drugs can inhibit the development of atherosclerotic lesions by inhibiting the expression level of the GAS6 protein. furthermore
It can be used to aid in tumor diagnosis and prognosis by measuring the expression level of GAS6 protein. For example, a low-expression GAS6 protein may predict a worse prognosis and greater tumor aggressiveness.
Expression level of GAS6 protein is related to tumor genesis, development and prognosis. For example, in patients with non-small cell lung cancer, low expression of the GAS6 protein was associated with poorer survival and higher metastasis rates. In addition, GAS6 protein can also serve as a biomarker to predict tumor response to specific treatments.
Customer Reviews (3)
Write a reviewGAS6 is a treasure in the field of scientific research due to its high catalytic efficiency, high safety and high expression level.
The short half-life and high clearance of GAS6 make its action more rapid and transient, allowing for a rapid therapeutic effect.
Green production process of GAS6 is very advanced and uses the most environmentally friendly production process and is very environmentally friendly.
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