"TFB1M" Related Products

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Recombinant Human Transcription Factor B1, Mitochondrial, His-tagged

Cat. No.: TFB1M-1785H
Product Overview: Recombinant humanTFB1M protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography.
Description: TFB1M belongs to themethyltransferase superfamily. TFB1M is a dimethyltransferase that methylatesmitochondrial 12S rRNA at the conserved stem loop. This protein also is partof the basal mitochondrial transcription complex and is necessary formitochondrial gene expression. TFB1M stimulates transcription independentlyof the methyltransferase activity.
Concentration: 0.5 mg/ml
Source: Human
Host: E.coli
Form: Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, with 20% glycerol, 0.1M NaCl and1mM DTT.
Purity: > 90% by SDS -PAGE
Sequence: 28-346 amino acids:MGSSHHHHHH SSGLVPRGSH MQAAKQLSQN FLLDLRLTDK IVRKAGNLTN AYVYEVGPGP GGITRSILNADVAELLVVEK DTRFIPGLQM LSDAAPGKLR IVHGDVLTFK VEKAFSESLK RPWEDDPPNV HIIGNLPFSVSTPLIIKWLE NISCRDGPFV YGRTQMTLTF QKEVAERLAA NTGSKQRSRL SVMAQYLCNV RHIFTIPGQAFVPK
Molecular Mass: 38.8 kDa.
Applications: SDS-PAGE
Storage: Storeat 4 deg C for short term storage. Aliquot and store at -20 deg C or -70 degC for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: TFB1M
Gene Name: TFB1M transcription factor B1,mitochondrial [ Homo sapiens ]
Synonyms: TFB1M;transcription factor B1, mitochondrial; CGI75; mtTFB;CGI-75; mtTFB1; dimethyladenosine transferase 1, mitochondrial; hTFB1M;h-mtTFB1; mitochondrial 12S rRNA dimethylase 1; mitochondrialdimethyladenosine transferase 1; homolog of yeast mitochondrial transcriptionfactor B; S-adenosylmethionine-6-N", N"-adenosyl(rRNA) dimethyltransferase 1;Dimethyladenosinetransferase 1, mitochondrial; Mitochondrial 12S rRNA dimethylase 1; Mitochondrialtranscription factor B1; h-mtTFB;S-adenosylmethionine-6-N",N"-adenosyl(rRNA) dimethyltransferase 1; EC 2.1.1.- ; OTTHUMP00000017473
Gene ID: 51106
mRNA Refseq: NM_057104
Protein Refseq: NP_016020
MIM: 607033
UniProt ID: Q8WVM0
Chromosome Location: 6q25.1-q25.3
Pathway: Energy Metabolism;Mitochondrial Gene Expression
Function: DNA binding; protein binding;methyltransferase activity; rRNA (adenine-N6, N6)-dimethyltransferaseactivity; transferase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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