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Recombinant Human Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7)

Cat.No.: PPBP-339H
ProductOverview: Recombinanthuman PPBP protein was expressed in E. coli and purified by usingconventional chromatograph.
Description: PPBP, also known aschemokine (C-X-C motif) ligand 7 (CXCL7), is a platelet-derived growth factorthat belongs to the alpha-chemokine family, It is a protein that is releasedin large amounts from platelets following their activation. It stimulatesvarious processes including mitogenesis, synthesis of extracellular matrix,glucose metabolism and synthesis of plasminogen activator.
Concentration: 1mg/ml
Source: Human
Host: E.coli
Form: Supplied as a liquidin 20mM Tris-HCl buffer, pH 7.5, containing 10% glycerol and 1mM DTT.
Purity: >90% by SDS - PAGE
Sequence: 35-128amino acids: MSSTKGQTKR NLAKGKEESL DSDLYAELRC MCIKTTSGIH PKNIQSLEVIGKGTHCNQVE VIATLKDGRK ICLDPDAPRI KKIVQKKLAG DESAD
MolecularMass: 10.3 kDa (95aa),confirmed by MALDI-TOF.
Applications: SDS-PAGE
Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: PPBP
Gene Name: PPBP pro-platelet basic protein(chemokine (C-X-C motif) ligand 7) [ Homo sapiens ]
Synonyms: PPBP; pro-plateletbasic protein (chemokine (C-X-C motif) ligand 7); PBP; TC1; TC2; TGB; LDGF;MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; SCAR10; THBGB1;Beta-TG; CTAPIII; CTAP-III; PPBP; platelet basic protein; thrombocidin 1;thrombocidin 2; OTTHUMP00000160477; b-TG1; NAP-2-L1; beta-thromboglobulin;CXC chemokine ligand 7; C-X-C motif chemokine 7; thromboglobulin, beta-1;small inducible cytokine B7; small-inducible cytokine B7; leukocyte-derivedgrowth factor; low-affinity platelet factor IV; neutrophil-activating peptide2; neutrophil-activating peptide-2; macropha- ge-derived growth factor;connective tissue-activating peptide III; small inducible cytokine subfamilyB, member 7; Macrophage-derived growth factor; Small-inducible cytokine B7;Leukocyte-derived growth factor
Gene ID: 5473
mRNA Refseq: NM_002704
Protein Refseq: NP_002695
MIM: 121010
UniProt ID: P02775
Chromosome Location: 4q12-q13
Pathway: Chemokinereceptors bind chemokines; Chemokine signaling pathway; Class A/1(Rhodopsin-like receptors); Cytokine-cytokine receptor interaction
Function: chemokine activity;glucose transmembrane transporter activity; growth factor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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