Recombinant Human Secreted Phosphoprotein 1 SPP1-5130H

Recombinant Human Secreted Phosphoprotein 1

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human Secreted Phosphoprotein 1

Recombinant Human Secreted Phosphoprotein 1

SPP1 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : SPP1-5130H
Product Overview : Recombinant human SPP1expressed by 293cells is a 60-65 kDa Osteopontin protein.
Description : SPP1 is a secreted glycoprotein thatfunctions as a ligand to alphavbeta3 integrin and possibly other receptors.It binds tightly to hydroxyapatite and can act as a structural component ofthe extracellular mineralized matrix. SPP1 is initially secreted as a 298amino acid protein, which is subject to multiple post-translationalmodifications including glycosylation, phosphorylation, and specificproteolytic cleavages into various smaller molecular weight fragments.
Source : Human
Host : 293 cells
Form : Supplied as alyophilized powder. Reconstitute in water to a concentration of 0.1-1.0mg/ml.
Purity : > 97% pure by SDS PAGE and HPLC
Sequence : Region of Osteopontin proteincorresponding to amino acids IPVKQADSGS SEEKQLYNKY PDAVATWLNP DPSQKQNLLAPQNAVSSEET NDFKQETLPS KSNESHDHMD DMDDEDDDDH VDSQDSIDSN DSDDVDDTDD SHQSDESHHSDESDELVTDF PTDLPATEVF TPVVPTVDTY DGRGDSVVYG LRSKSKKFRR PDIQYPDATD EDITSHMES
Molecular Mass : 60-65 kDa
Endotoxin Levels : Endotoxin level is less than 0.1 ngper ug (1 EU/ug).
Bioactivity : Determined by its ability tochemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
Applications : Numerous applications are possiblewith this product and should be tested by the end user under their ownlaboratory conditions.
Storage : Store at 4 deg Cuntil reconstitution. Following reconstitution aliquot and freeze at -20 degC for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol : SPP1
Rendering based on PDB 3CXD. :

Gene Name : SPP1 secreted phosphoprotein 1 [ Homo sapiens]
Synonyms : SPP1; secretedphosphoprotein 1; OPN; BNSP; BSPI; ETA-1; MGC110940; osteopontin; SPP-1; Uropontin; Nephropontin; osteopontin-C;osteopontin-D; OTTHUMP00000161173; OTTHUMP00000161174; OTTHUMP00000218555; OTTHUMP00000218556;SPP1/CALPHA1 fusion; bone sialoprotein 1; bone sialoprotein I; urinary stoneprotein; early T-lymphocyte activation 1; secreted phosphoprotein-1(osteopontin, bone sialoprotein); osteopontin/immunoglobulin alpha 1 heavychain constant region fusion protein; secreted phosphoprotein 1 (osteopontin,bone sialoprotein I, early T-lymphocyte activation 1)
Gene ID : 6696
mRNA Refseq : NM_000582
Protein Refseq : NP_000573
MIM : 166490
UniProt ID : P10451
Chromosome Location : 4q22.1
Pathway : Direct p53 effectors;ECM-receptor interaction; Endochondral Ossification; FGF signaling pathway;Focal Adhesion; Integrin cell surface interactions; Osteoclast Signaling;Osteopontin Signaling; Osteopontin-mediated events; Signaling by PDGF; TGFBeta Signaling Pathway; Toll-like receptor signaling pathway
Function : cytokineactivity; extracellular matrix binding

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy