Native Bovine Plasminogen


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Native Bovine Plasminogen

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Cat.No. : PLG-1867B
Product Overview : Native Bovine PLGwas expessed in bovine heart. Its molecular weight is 85000 Dalton
Description : Plasminogen (PLG) isa circulating zymogen that is converted to the active enzyme Plasmin bycleavage of the peptide bond between Arg-560 and Val-561, which is mediatedby Urokinase (uPA/PLAU) and Tissue PLG Activator (tPA/PLAT). The mainfunction of Plasmin is to dissolve Fibrin blood clots. Plasmin, like Trypsin,belongs to the family of serine proteases Fibrin is a cofactor forPlasminogen activation by tPA. Urokinase PLG Activator Receptor (uPAR) is acofactor for PLG activation by uPA. Plasmin is inactivated byAlpha-2-Antiplasmin, a serine protease inhibitor (serpin).
Source : Mouse Plasma
Species : Bovine
Form : Frozen Liquid in 0.1M HEPES pH 7.4 + 0.1 M NaCl
Molecular Mass : 85000 Dalton
Concentration : 5.0 mg/ml
Gene Name : PLG plasminogen [ Bos taurus ]
Official Symbol : PLG
Synonyms : LPAplasminogen; plasmin; lipoprotein, Lp(a)
Gene ID : 280897
mRNA Refseq : NM_173951
Protein Refseq : NP_776376
UniProt ID : P06868
Chromosome Location : chromosome: 9
Pathway : Activation of Matrix Metalloproteinases, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Dissolution of Fibrin Clot, organism-specific biosystem
Function : protein binding; serine-type endopeptidase activity

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