Native Human Ribonuclease, RNase A Family, 3


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Native Human Ribonuclease, RNase A Family, 3

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Cat. No. : RNASE3-5318H
Product Overview : NativeHuman RNASE3 was expessed in Human Eosinophils. Itsmolecular weight is 18000-22000 Dalton (3 glycosolated forms exists).
Description : Native human RNASE3is a secretory ribonuclease found in eosinophilic leukocytes and involved inthe innate immune system. Its cytotoxic activity is effective against a widerange of pathogens, suggesting a relatively non-specific mechanism of action.
Form : Liquid in 50 mMammonium acetate, pH 4.7 + 0.2 M NaCl
Source : HumanEosinophils
Concentration : Typically>1.0 mg/mL
Molecular Weight : 18-22kDa (3 glycosolated forms exists)
Purity : >98% by SDS-PAGE
Storage : Store at 2-4°C.
OfficialSymbol : RNASE3
Pathways : Asthma
PDB rendering based on 1dyt. :

Gene Name : RNASE3 ribonuclease, RNase A family, 3 [ Homosapiens ]
Synonyms : RNASE3; ribonuclease,RNase A family, 3; ECP; RNS3; eosinophil cationic protein; EC 3.1.27.-; Eosinophilcationic protein; RNase 3; Ribonuclease 3
Gene ID : 6037
mRNA Refseq : NM_002935
Protein Refseq : NP_002926
MIM : 131398
UniProt ID : P12724
Chromosome Location : 14q24-q31
Function : endonucleaseactivity; hydrolase activity; nucleic acid binding; pancreatic ribonucleaseactivity; ribonuclease activity

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