Native Human Coagulation Factor VII (serum prothrombin conversion accelerator)

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Native Human Coagulation Factor VII (serum prothrombin conversion accelerator)

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Cat. No. : F7-5303H
Product Overview : Native Human F7 was expressedin Human Plasma.
Description : F7 is one of the proteinsthat causes blood to clot in the coagulation cascade. It is an enzyme of theserine protease class. It is often used unlicensed in severe uncontrollablebleeding, although there has been safety concerns.
Source : Human Plasma
Form : Liquid in 50% (v/v)glycerol/H2O.
SpecificActivity : Measured in a F7clotting assay.
Concentration : 5.0 mg/ml
Molecular Weight : 50 kDa
Storage : Store in working aliquots at -20°C. Avoidrepeated freeze-thaw cycles.
Pathways : BMAL1: CLOCK/NPAS2 Activities GeneExpression; Blood Clotting Cascade; Circadian Clock; Complement andCoaqulation Cascades; Extrinsic Pathway; Formation of Fibrin Clot (ClottingCascade); Gamma-carboxylation of protein precursors; Gamma-carboxylation, transport,and amino-terminal cleavage of proteins; Hemostasis; Metabolism of proteins;Post-translational protein modification; Removal of aminoterminal propeptidesfrom gamma-carboxylation proteins; Selenium Pathway; Transport ofgamma-carboxylated protein precursors from the endoplasmic reticulum to theGolqi apparatus
Anchoring of coagulationfactor VIIa to the membrane through its Gla domain. :

Gene Name : F7coagulation factor VII (serum prothrombin conversion accelerator) [ Homo sapiens ]
Official Symbol : F7
Synonyms : F7; coagulation factor VII (serum prothrombin conversionaccelerator); eptacog alfa; factor VII; FVII coagulation protein; OTTHUMP00000018733;OTTHUMP00000018734; OTTHUMP000000199423; Coagulation factor VII; EC3.4.21.21; Proconvertin; Serum prothrombin conversion accelerator; SPCA; Eptacogalfa; Factor VII light chain; Factor VII heavy chain; proconvertin; EC 3.4.21
Gene ID : 2155
mRNA Refseq : NM_000131
Protein Refseq : NP_000122
MIM : 613878
UniProt ID : P08709
Chromosome Location : 13q34
Function : calcium ion binding;glycoprotein binding; peptidase activity; receptor binding; serine-typeendopeptidase activity; serine-type peptidase activity

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