"CKM" Related Products

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Native Human creatine kinase, muscle

Cat. No.: CKM-5306H
Product Overview: Native human CKM was expressedin Human skeletal muscle and its Isoenzyme is 100% CKMM, no CKBB orCKMB detected.
Description: The protein encodedby this gene is a cytoplasmic enzyme involved in energy homeostasis and is animportant serum marker for myocardial infarction. The encoded proteinreversibly catalyzes the transfer of phosphate between ATP and variousphosphogens such as creatine phosphate. It acts as a homodimer in striatedmuscle as well as in other tissues, and as a heterodimer with a similar brainisozyme in heart. The encoded protein is a member of the ATP:guanidophosphotransferase protein family.
Form: Liquid in 50%Glycerol + 50 mM Tris + 2 mM DTT, pH 7.5.
Source: Human skeletalmuscle
Purity: > 96% asdetermined by SDS-PAGE analysis
Specific Activity: Typically >1000u/ml @ 37°C
Concentration: 22.3 mg/ml
Storage: Stable for 1 year at2-4°C.
Pathways: Arginine and proline metabolism; Creatinemetabolism; Creatine pathway; Metabolic pathways; Metabolism of amino acidsand derivatives; Regulation of retinoblastoma protein; Urea cycle andmetabolism of amino groups; creatine-phosphate biosynthesis
Gene Name: CKM creatine kinase, muscle [ Homosapiens ]
Official Symbol: CKM
Synonyms: CKM; creatine kinase, muscle; CKMM; M-CK; creatinekinase M-type; creatine kinase-M; creatine kinase M chain; Creatine kinase M-type; Creatine kinase M chain; EC 2.7.3.2
Gene ID: 1158
mRNA Refseq: NM_001824
Protein Refseq: NP_001815
MIM: 123310
UniProt ID: P06732
Chromosome Location: 19q13.2-q13.3
Function: ATPbinding; creatine kinase activity; nucleotide binding

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