Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 1


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Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 1

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Cat. No. : Serpine1-5319M
Product Overview : Recombinant Mouse Serpine1was expressed in E. coli (PAI-1) + Insect cell culture (tPA).
Description : Mouserecombinant Serpine1complexedto tPA. Mouse sc-tPA is reacted with an excess of mouse Serpine1 stablemutant at physiological pH. The resulting 1:1 molar complex is purified fromthe remaining Serpine1 by affinity chromatography with immobilizedantibodies to mouse tPA.
Source : E. coli (PAI-1) +Insect cell culture (tPA)
Species : Mouse
Form : Frozen liquid in0.4M HEPES + 0.1M NaCl, pH 7.4.
Purity : > 95% by SDS-PAGEanalysis.
Endotoxin Level : < 0.1 ng/μg ofprotein.
Concentration : 1.0 mg/ml
Storage : Store at-80°C. Stable at -80°C for 1 year from delivery. Avoid repeated freeze-thaw cycles.
OfficialSymbol : Serpine1
PAI-1 incomplex with the SMB domain of Vitronectin PDB 1OC0 :

Gene Name : Serpine1 serine (or cysteine)peptidase inhibitor, clade E, member 1 [ Mus musculus ]
Synonyms : Serpine1; serine (orcysteine) peptidase inhibitor, clade E, member 1; PAI1; PAI-1; Planh1;plasminogen activator inhibitor 1; PAI; serpin E1; plasminogen activatorinhibitor, type I; endothelial plasminogen activator inhibitor; nexin,plasminogen activator inhibitor type 1; serine (or cysteine) proteinaseinhibitor, clade E, member 1; Plasminogen activator inhibitor-1 precursor(PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)
Gene ID : 18787
mRNA Refseq : NM_008871
Protein Refseq : NP_032897
UniProt ID : P22777
Chromosome Location : 5 G2
Pathway : Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Complement and coagulation cascades; Senescence andAutophagy; TGF Beta Signaling Pathway; p53 signaling pathway
Function : protease binding;protein binding; serine-type endopeptidase inhibitor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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