Recombinant Rat Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1 Serpine1-5310R

Recombinant Rat Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1

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Recombinant Rat Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1

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Cat. No. : Serpine1-5310R
Product Overview : Recombinant Rat Serpine1was expressed in Rat Plasma.
Description : Serpine1 is theprincipal inhibitor of Tissue Plasminogen Activator(tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis.It is a serine protease inhibitor (serpin) protein (SERPINE1). Serpine1 ismainlyproducedby the endothelium, but is also secreted by other tissue types, such asadiposetissue.
Source : Rat Plasma
Species : Rat
Form : Frozen Liquid
Concentration : < 0.1 ng/mL PAI1Antigen.
Storage : Store at-70°C.
OfficialSymbol : Serpine1
PAI-1 incomplex with the SMB domain of Vitronectin PDB 1OC0 :

Gene Name : Serpine1 serpin peptidaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1[ Rattus norvegicus ]
Synonyms : Serpine1; serpinpeptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1),member 1; Pai1;PAI1A; Planh; Pai1aa; RATPAI1A; plasminogen activator inhibitor 1; PAI;PAI-1; serpin E1; endothelial plasminogen activator inhibitor; serine (orcysteine) proteinase inhibitor, member 1; serine (or cysteine) peptidaseinhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor,clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin,plasminogen activator inhibitor type 1), member 1
Gene ID : 24617
mRNA Refseq : NM_012620
Protein Refseq : NP_036752
Chromosome Location : 12q11-q12
Pathway : Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Dissolution of Fibrin Clot; Hemostasis; Plateletactivation; Platelet degranulation; Response to elevated platelet cytosolicCa2+; Senescence and Autophagy; TGF Beta Signaling Pathway; p53 pathway; p53signaling pathway
Function : peptidase inhibitoractivity; protease binding; receptor binding; contributes_to receptorbinding; serine-type endopeptidase inhibitor activity

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