Recombinant Rat Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1 Serpine1-5310R

Recombinant Rat Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1

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Specification Gene Information Related Products

Cat. No. :	Serpine1-5310R
Product Overview :	Recombinant Rat Serpine1was expressed in Rat Plasma.
Description :	Serpine1 is theprincipal inhibitor of Tissue Plasminogen Activator(tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis.It is a serine protease inhibitor (serpin) protein (SERPINE1). Serpine1 ismainlyproducedby the endothelium, but is also secreted by other tissue types, such asadiposetissue.
Source :	Rat Plasma
Species :	Rat
Form :	Frozen Liquid
Concentration :	< 0.1 ng/mL PAI1Antigen.
Storage :	Store at-70°C.
OfficialSymbol :	Serpine1
PAI-1 incomplex with the SMB domain of Vitronectin PDB 1OC0 :

Gene Name :	Serpine1 serpin peptidaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1[ Rattus norvegicus ]
Synonyms :	Serpine1; serpinpeptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1),member 1; Pai1;PAI1A; Planh; Pai1aa; RATPAI1A; plasminogen activator inhibitor 1; PAI;PAI-1; serpin E1; endothelial plasminogen activator inhibitor; serine (orcysteine) proteinase inhibitor, member 1; serine (or cysteine) peptidaseinhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor,clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin,plasminogen activator inhibitor type 1), member 1
Gene ID :	24617
mRNA Refseq :	NM_012620
Protein Refseq :	NP_036752
Chromosome Location :	12q11-q12
Pathway :	Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Dissolution of Fibrin Clot; Hemostasis; Plateletactivation; Platelet degranulation; Response to elevated platelet cytosolicCa2+; Senescence and Autophagy; TGF Beta Signaling Pathway; p53 pathway; p53signaling pathway
Function :	peptidase inhibitoractivity; protease binding; receptor binding; contributes_to receptorbinding; serine-type endopeptidase inhibitor activity