Cat. No.: | Serpine1-5310R |
Product Overview: | Recombinant Rat Serpine1was expressed in Rat Plasma. |
Description: | Serpine1 is theprincipal inhibitor of Tissue Plasminogen Activator(tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis.It is a serine protease inhibitor (serpin) protein (SERPINE1). Serpine1 ismainlyproducedby the endothelium, but is also secreted by other tissue types, such asadiposetissue. |
Source: | Rat Plasma |
Species: | Rat |
Form: | Frozen Liquid |
Concentration: | < 0.1 ng/mL PAI1Antigen. |
Storage: | Store at-70°C. |
OfficialSymbol: | Serpine1 |
Gene Name: | Serpine1 serpin peptidaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1[ Rattus norvegicus ] |
Synonyms: | Serpine1; serpinpeptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1),member 1; Pai1;PAI1A; Planh; Pai1aa; RATPAI1A; plasminogen activator inhibitor 1; PAI;PAI-1; serpin E1; endothelial plasminogen activator inhibitor; serine (orcysteine) proteinase inhibitor, member 1; serine (or cysteine) peptidaseinhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor,clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin,plasminogen activator inhibitor type 1), member 1 |
Gene ID: | 24617 |
mRNA Refseq: | NM_012620 |
Protein Refseq: | NP_036752 |
Chromosome Location: | 12q11-q12 |
Pathway: | Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Dissolution of Fibrin Clot; Hemostasis; Plateletactivation; Platelet degranulation; Response to elevated platelet cytosolicCa2+; Senescence and Autophagy; TGF Beta Signaling Pathway; p53 pathway; p53signaling pathway |
Function: | peptidase inhibitoractivity; protease binding; receptor binding; contributes_to receptorbinding; serine-type endopeptidase inhibitor activity |
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