"Serpine1" Related Products


Recombinant Rat Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1

Cat. No.: Serpine1-5310R
Product Overview: Recombinant Rat Serpine1was expressed in Rat Plasma.
Description: Serpine1 is theprincipal inhibitor of Tissue Plasminogen Activator(tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis.It is a serine protease inhibitor (serpin) protein (SERPINE1). Serpine1 ismainlyproducedby the endothelium, but is also secreted by other tissue types, such asadiposetissue.
Source: Rat Plasma
Species: Rat
Form: Frozen Liquid
Concentration: < 0.1 ng/mL PAI1Antigen.
Storage: Store at-70°C.
OfficialSymbol: Serpine1
Gene Name: Serpine1 serpin peptidaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1[ Rattus norvegicus ]
Synonyms: Serpine1; serpinpeptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1),member 1; Pai1;PAI1A; Planh; Pai1aa; RATPAI1A; plasminogen activator inhibitor 1; PAI;PAI-1; serpin E1; endothelial plasminogen activator inhibitor; serine (orcysteine) proteinase inhibitor, member 1; serine (or cysteine) peptidaseinhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor,clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin,plasminogen activator inhibitor type 1), member 1
Gene ID: 24617
mRNA Refseq: NM_012620
Protein Refseq: NP_036752
Chromosome Location: 12q11-q12
Pathway: Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Dissolution of Fibrin Clot; Hemostasis; Plateletactivation; Platelet degranulation; Response to elevated platelet cytosolicCa2+; Senescence and Autophagy; TGF Beta Signaling Pathway; p53 pathway; p53signaling pathway
Function: peptidase inhibitoractivity; protease binding; receptor binding; contributes_to receptorbinding; serine-type endopeptidase inhibitor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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