Cat. No.:	Serpine1-5310R
Product Overview:	Recombinant Rat Serpine1was expressed in Rat Plasma.
Description:	Serpine1 is theprincipal inhibitor of Tissue Plasminogen Activator(tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis.It is a serine protease inhibitor (serpin) protein (SERPINE1). Serpine1 ismainlyproducedby the endothelium, but is also secreted by other tissue types, such asadiposetissue.
Source:	Rat Plasma
Species:	Rat
Form:	Frozen Liquid
Concentration:	< 0.1 ng/mL PAI1Antigen.
Storage:	Store at-70°C.
OfficialSymbol:	Serpine1

Gene Name:	Serpine1 serpin peptidaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1[ Rattus norvegicus ]
Synonyms:	Serpine1; serpinpeptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1),member 1; Pai1;PAI1A; Planh; Pai1aa; RATPAI1A; plasminogen activator inhibitor 1; PAI;PAI-1; serpin E1; endothelial plasminogen activator inhibitor; serine (orcysteine) proteinase inhibitor, member 1; serine (or cysteine) peptidaseinhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor,clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin,plasminogen activator inhibitor type 1), member 1
Gene ID:	24617
mRNA Refseq:	NM_012620
Protein Refseq:	NP_036752
Chromosome Location:	12q11-q12
Pathway:	Adipogenesis; BloodClotting Cascade; Chagas disease (American trypanosomiasis); Complement andCoagulation Cascades; Dissolution of Fibrin Clot; Hemostasis; Plateletactivation; Platelet degranulation; Response to elevated platelet cytosolicCa2+; Senescence and Autophagy; TGF Beta Signaling Pathway; p53 pathway; p53signaling pathway
Function:	peptidase inhibitoractivity; protease binding; receptor binding; contributes_to receptorbinding; serine-type endopeptidase inhibitor activity

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