Native Human Serpin Peptidase Inhibitor, Clade F (alpha-2 antiplasmin, pigment epithelium derived factor), Member 2
Cat.No. : | SERPINF2-5338H |
Product Overview : | Native human SERPINF2expressed by Human Plasma is a 70.0 kDa protein. |
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- Gene Information
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Cat. No. : | SERPINF2-5338H |
Description : | SERPINF2 is a memberof the serpin family of serine protease inhibitors and is a major inhibitorof Plasmin. Consequently, SERPINF2 has a major role in regulating theCoagulation Cascade. Mutations in SERPINF2 result in Alpha-2-AntiplasminDeficiency, a rare coagulation disorder characterized by unrestrainedfibrinolytic activity and severe hemorrhagic diathesis. Individuals with thiscondition may receive therapeutic SERPINF2 prior to surgery to preventpostoperative hemorrhaging. |
Source : | Human Plasma |
Species : | Human |
Form : | Lyophilized from0.02 M Bis-Tris + 0.2 M NaCl, pH 6.4. |
Molecular Weight : | 70.0 kDa |
Concentration : | 1.0 mg/ml |
Purity : | > 95% by SDS-PAGE. |
Specific Activity : | 19.9IU/mg |
Reconstitution : | Centrifugevial prior to opening. Reconstitute with sterile distilled waterto originalvolume(0.559 mL). |
Storage : | Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | SERPINF2 |
Gene Name : | SERPINF2 serpin peptidaseinhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor),member 2 [ Homo sapiens ] |
Synonyms : | SERPINF2; serpinpeptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derivedfactor), member 2; AAP; API; PLI; A2AP; ALPHA-2-PI; alpha-2-antiplasmin; serpinF2; alpha-2-AP; OTTHUMP00000115656; OTTHUMP00000197008; OTTHUMP00000197009; alpha-2-plasmininhibitor; serine (or cysteine) proteinase inhibitor, clade F (alpha-2antiplasmin, pigment epithelium derived factor), member 2 |
Gene ID : | 5345 |
mRNA Refseq : | NM_000934 |
Protein Refseq : | NP_000925 |
MIM : | 613168 |
UniProt ID : | P08697 |
Chromosome Location : | 17p13 |
Pathway : | Blood ClottingCascade; Complement and Coagulation Cascades; Dissolution of Fibrin Clot;Hemostasis; Platelet activation; Platelet degranulation; Response to elevatedplatelet cytosolic Ca2+ |
Function : | endopeptidaseinhibitor activity; protease binding; protein binding; serine-typeendopeptidase inhibitor activity |
Products Types
◆ Recombinant Protein | ||
SERPINF2-397R | Recombinant Rabbit SERPINF2 Protein, His-tagged | +Inquiry |
Serpinf2-5793M | Recombinant Mouse Serpinf2 Protein, Myc/DDK-tagged | +Inquiry |
SERPINF2-533R | Recombinant Rat SERPINF2 Protein, His-tagged | +Inquiry |
SERPINF2-91H | Recombinant Human SERPINF2 protein | +Inquiry |
Serpinf2-27M | Recombinant Mouse Serpinf2, His-tagged | +Inquiry |
◆ Native Protein | ||
SERPINF2-27292TH | Native Human SERPINF2 | +Inquiry |
SERPINF2-27145TH | Native Human SERPINF2 | +Inquiry |
◆ Lysates | ||
SERPINF2-2750MCL | Recombinant Mouse SERPINF2 cell lysate | +Inquiry |
SERPINF2-2445HCL | Recombinant Human SERPINF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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