Recombinant Human Activin A Receptor, Type IB, GST-tagged
Cat.No. : | ACVR1B-5295H |
Product Overview : | Recombinant human ACVR1Bprotein is catalytic domain (aa 150-505) and N-terminal GST-tagged, expressedin insect cells. |
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- Gene Information
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Cat. No. : | ACVR1B-5295H |
Description : | ACVR1B is a serine/threonine kinase involved insignal transduction and cellular communication; several truncated ACVR1Bisoforms have been reported to be exclusively expressed in human pituitarytumors and mutations of ACVR1B have been observed in pancreaticadenocarcinomas. |
Source : | Insect cells |
Species : | Human |
Form : | Liquid in 50 mMTris-HCl (pH 7.5) + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT+ 50% glycerol. |
Molecular Weight : | 68.2 kDa |
Purity : | > 85% |
Specific Activity : | > 250 nmolphosphate transferred to Casein substrate/min/mg. |
Storage : | Stable for 6 monthsat -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | ACVR1B |
Gene Name : | ACVR1B activin A receptor, type IB[ Homo sapiens ] |
Synonyms : | ACVR1B; activin Areceptor, type IB; ALK4; SKR2; ACTRIB; ACVRLK4; activin receptor type-1B;OTTHUMP00000237285; OTTHUMP00000237286; OTTHUMP00000237287;OTTHUMP00000237289; OTTHUMP00000241624; activin receptor-like kinase 4; activinA receptor, type II-like kinase 4; serine/threonine-protein kinase receptorR2; EC 2.7.11.30 |
Gene ID : | 91 |
mRNA Refseq : | NM_004302 |
Protein Refseq : | NP_004293 |
MIM : | 601300 |
UniProt ID : | P36896 |
Chromosome Location : | 12q13 |
Pathway : | Cytokine-cytokinereceptor interaction; Developmental Biology; MAPK signaling pathway;Regulation of Signaling by NODAL; Signaling by NODAL |
Function : | ATP binding; SMADbinding; contributes to activin binding; activin receptor activity, type I;contributes to activin-activated receptor activity; contributes to growthfactor binding; metal ion binding; nucleotide binding; protein binding;protein serine/threonine kinase activity; receptor activity; transforminggrowth factor beta-activated receptor activity; transmembrane receptorprotein serine/threonine kinase activity; ubiquitin protein ligase binding |
Products Types
◆ Recombinant Protein | ||
ACVR1B-165H | Recombinant Human ACVR1B Protein, His (Fc)-Avi-tagged | +Inquiry |
Acvr1b-1M | Recombinant Mouse Acvr1b Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVR1B-148R | Recombinant Rat ACVR1B Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVR1B-59R | Recombinant Rhesus Macaque ACVR1B Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVR1B-082H | Recombinant Human ACVR1B Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
ACVR1B-2130HCL | Recombinant Human ACVR1B cell lysate | +Inquiry |
ACVR1B-1206RCL | Recombinant Rat ACVR1B cell lysate | +Inquiry |
ACVR1B-1356CCL | Recombinant Cynomolgus ACVR1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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