Gene Name: |
ACVR1B activin A receptor, type IB[ Homo sapiens ] |
Synonyms: |
ACVR1B; activin Areceptor, type IB; ALK4; SKR2; ACTRIB; ACVRLK4; activin receptor type-1B;OTTHUMP00000237285; OTTHUMP00000237286; OTTHUMP00000237287;OTTHUMP00000237289; OTTHUMP00000241624; activin receptor-like kinase 4; activinA receptor, type II-like kinase 4; serine/threonine-protein kinase receptorR2; EC 2.7.11.30 |
Gene ID: |
91 |
mRNA Refseq: |
NM_004302 |
Protein Refseq: |
NP_004293 |
MIM: |
601300 |
UniProt ID: |
P36896 |
Chromosome Location: |
12q13 |
Pathway: |
Cytokine-cytokinereceptor interaction; Developmental Biology; MAPK signaling pathway;Regulation of Signaling by NODAL; Signaling by NODAL |
Function: |
ATP binding; SMADbinding; contributes to activin binding; activin receptor activity, type I;contributes to activin-activated receptor activity; contributes to growthfactor binding; metal ion binding; nucleotide binding; protein binding;protein serine/threonine kinase activity; receptor activity; transforminggrowth factor beta-activated receptor activity; transmembrane receptorprotein serine/threonine kinase activity; ubiquitin protein ligase binding |