Native Human Ferritin, Light Polypeptide


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Native Human Ferritin, Light Polypeptide

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Cat. No. : FTL-673H
Product Overview : Native Human FTL isprepared from Human Liver.
Description : HumanFTL is a globular protein found mainly in the liver, which can store about4500 iron ions in a hollow shell made of 24 identical subunits. Inside thehuman FTL shell, iron ions form crystallites together with phosphate andhydroxide ions. Human Serum FTL levels are measured in patients as part ofthe iron studies workup for anemia and for restless leg syndrome. Human FTLlevels have a direct correlation with the total amount of iron stored in thebody. Human FTL level(s) are also indicative of the erosion of iron storesduring pregnancy.
Form : Sodium chloridebuffer, pH 7.5.
Source : Human Liver
Molecular Weight : 440 kDa
Purity : > 98%
Concentration : > 1.0 mg/ml
Biological Activity : > 1.0 mg/ml
Storage : Store at 2-4°C.Stable for 2 years from delivery. Avoid repeated freeze-thaw cycles.
Pathways : Clathrin derived vesicle budding; GolgiAssociated Vesicle Biogenesis; Membrane Trafficking; Mineral absorption;Porphyrin and chlorophyll metabolism; trans-Golgi Network Vesicle Budding
PDB rendering based on 2ffx. :

Gene Name : FTL ferritin, light polypeptide[ Homo sapiens ]
Official Symbol : FTL
Synonyms : FTL; ferritin, lightpolypeptide; NBIA3; MGC71996; ferritin, light polypeptide; ferritin Lsubunit; ferritin L-chain; ferritin light chain; ferritin lightpolypeptide-like 3
Gene ID : 2512
mRNA Refseq : NM_000146
Protein Refseq : NP_000137
MIM : 134790
UniProt ID : P02792
Chromosome Location : 19q13.3-q13.4
Function : binding;ferric iron binding; identical protein binding; iron ion binding;oxidoreductase activity

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