Recombinant Human Interferon, Alpha 1 IFNA1-5280H

Recombinant Human Interferon, Alpha 1

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Recombinant Human Interferon, Alpha 1

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Cat. No. : IFNA1-5280H
Product Overview : Recombinant Human IFNA1is produced in E. coli.
Description : At least 23 different variants of IFNA1 areknown. The individual proteins have molecular masses between 19-26 kDa andconsist of proteins with lengths of 156-166 and 172 amino acids. All IFNA1subtypes possess a common conserved sequence region between amino acidpositions 115-151 while the amino-terminal ends are variable. Many IFNA1subtypes differ in their sequences at only one or two positions. Naturallyoccurring variants also include proteins truncated by 10 amino acids at thecarboxy-terminal end.
Source : E. coli
Species : Human
Form : Lyophilized from a0.2 um filtered solution in PBS, pH 7.4.
Purity : > 96% by SDS-PAGEand HPLC analyses.
Endotoxin Level : Less than 1EU/mL ofrHuIFN-α1b as determined by LAL method.
Biological Activity : Fully biologicallyactive when compared to standard. The specific activity as determined in aviral resistance assay was found to be no less than 1.0 x 108IU/mg.
Reconstitution : We recommend thatthis vial be briefly centrifuged prior to opening to bring the contents tothe bottom. Reconstitute in sterile distilled water or aqueous buffer to aconcentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned intoworking aliquots and stored at ≤20°C. Further dilutions should be made inappropriate buffered solutions.
Storage : This lyophilizedpreparation is stable at 2-8°C, but should be kept at -20°C for long termstorage, preferably desiccated. Upon reconstitution, the preparation is stablefor up to one week at 2-8°C. For maximal stability, apportion thereconstituted preparation into working aliquots and store at -20°C to -80°C.Avoid repeated freeze/thaw cycles.
OfficialSymbol : IFNA1
Gene Name : IFNA1 interferon, alpha 1 [ Homosapiens ]
Synonyms : IFNA1;interferon, alpha 1; IFL; IFN; IFNA; IFNA13; IFN-ALPHA;MGC138207; MGC138505; MGC138507; IFN-alphaD; interferon alpha-1/13; leIF D;IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; OTTHUMP00000021142;interferon alpha-D; interferon alpha 1b
Gene ID : 3439
mRNA Refseq : NM_024013
Protein Refseq : NP_076918
MIM : 139250
UniProt ID : P01562
Chromosome Location : 9p22
Pathway : Autoimmune thyroiddisease; Cytokine Signaling in Immune system; Cytokine-cytokine receptorinteraction; Cytosolic DNA-sensing pathway; Factors involved in megakaryocytedevelopment and platelet production; Hemostasis; Hepatitis C; Herpes simplexinfection; IL-2 Signaling Pathway; Immune System; Interferon Signaling

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