Native Human Cathepsin B
Cat.No. : | CTSB-5328H |
Product Overview : | Native Human CTSB was expressed in Human Liver. |
- Specification
- Gene Information
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Cat. No. : | CTSB-5328H |
Description : | CTSB, a cysteineproteinase, is located in lysosomes and is involved in tissue degradation andrestructuring. Specifically, CTSB is believed to be involved in theintracellular digestion of extracellular proteins taken up by endocytosis. |
Form : | Frozenliquid in a buffer of 0.05 M Sodium Acetate + 1 mM EDTA, pH 5.0. |
Molecular Weight : | 27.5 kDa |
Purity : | > 95% by SDS PAGE |
Source : | Human Liver |
Storage : | Productis stable at -80°C for 3 years. |
OfficialSymbol : | CTSB |
Pathways : | Antigen processing and presentation;Lysosome |
Gene Name : | CTSBcathepsin B [ Homo sapiens ] |
Synonyms : | CTSB; cathepsin B; APPS; CPSB; cathepsin B1; APP secretase; cycteinprotease; OTTHUMP00000116009; OTTHUMP00000229510; OTTHUMP00000229511; OTTHUMP00000229512;OTTHUMP00000229514; OTTHUMP00000229515; OTTHUMP00000229516; Amyloid precursorprotein secretase; EC 3.4.22.1; Cathepsin B; Cathepsin B1 |
Gene ID : | 1508 |
mRNA Refseq : | NM_001908 |
Protein Refseq : | NP_001899 |
MIM : | 116810 |
UniProt ID : | P07858 |
Chromosome Location : | 8p22 |
Function : | cysteine-typeendopeptidase activity; kininogen binding; peptidase activity; proteinbinding |
Products Types
◆ Recombinant Protein | ||
CTSB-175C | Recombinant Cynomolgus Monkey CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctsb-10530M | Recombinant Mouse Ctsb Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-911R | Recombinant Rhesus Macaque CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-3369H | Recombinant Human CTSB Protein, MYC/DDK-tagged | +Inquiry |
CTSB-2750H | Recombinant Human CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CTSB-26408TH | Native Human CTSB | +Inquiry |
CTSB-188B | Active Native Bovine Cathepsin B | +Inquiry |
◆ Lysates | ||
CTSB-1885MCL | Recombinant Mouse CTSB cell lysate | +Inquiry |
CTSB-3025HCL | Recombinant Human CTSB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2366 | Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCTSB affects extracellular matrix remodeling, relevant in joint diseases like osteoarthritis.
CTSB is implicated in neurodegenerative diseases, potentially contributing to protein aggregation and neuronal damage.
Variations in CTSB expression impact tissue repair processes and the development of fibrosis in various organs.
CTSB regulates apoptosis and cell survival, influencing cell fate decisions under stress or damage.
CTSB can influence cancer progression by modulating the tumor microenvironment and facilitating tumor cell invasion.
CTSB is involved in lysosomal protein degradation, essential for cellular waste disposal and recycling.
CTSB plays a role in inflammation, impacting immune cell function and inflammatory responses.
Customer Reviews (3)
Write a reviewExceptional protein engineering services, our trusted research partner.
Reliable protein crystallography, key for our structural biology research.
Swift protein quantification, improves data reliability in our work.
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