Native Human Coagulation Factor II (thrombin)
Cat.No. : | F2-5285H |
Product Overview : | Native Human F2 was expressedin human plasma. |
- Specification
- Gene Information
- Related Products
Cat. No. : | F2-5285H |
Description : | F2is proteolytically cleaved to form thrombin in the first step of thecoagulation cascade which ultimately results in the stemming of blood loss.F2 also plays a role in maintaining vascular integrity during development andpostnatal life. Mutations in F2 lead to various forms of thrombosis anddysprothrombinemia. |
Source : | Human plasma |
Form : | Liquidin 0.1 M NaH2PO4, pH 6.5. |
Concentration : | 5.0mg/ml |
Molecular Weight : | 34.3 kDa |
Specific Activity : | Determinedusing a fibrinogen clotting assay. |
Storage : | Store in workingaliquots at -20°C. Avoid repeated freeze-thaw cycles. |
Pathways : | Angiopoietinreceptor Tie2-mediated signaling; Blood Clotting Cascade; Cell surfaceinteractions at the vascular wall; Class A/1(Rhodopsin-like receptors); CommonPathway; Complement and Coaqulation Cascades; Diabetes pathways; FOXA2 andFOXA3 transcription factor networks; Extrinsic Pathway; Formation of FibrinClot (Clotting Cascade); Hemostasis; Intrinsic Pathway; Regulation of actincytoskeleton; Selenium Pathway; Signal Transduction |
Gene Name : | F2 coagulation factor II (thrombin) [ Homosapiens ] |
Official Symbol : | F2 |
Synonyms : | F2; coagulation factor II (thrombin); PT; prothrombin; serineprotease; OTTHUMP00000197117; OTTHUMP00000197118; OTTHUMP00000233661;prothrombin B-chain; EC 3.4.21.5; EC 3.4.21; Prothrombin; Coagulation factorII; Activation peptide fragment 1; Activation peptide fragment 2; Thrombinlight chain; Thrombin heavy chain |
Gene ID : | 2147 |
mRNA Refseq : | NM_000506 |
Protein Refseq : | NP_000497 |
MIM : | 176930 |
UniProt ID : | P00734 |
Chromosome Location : | 11p11 |
Function : | peptidaseactivity;protein binding; serine-type endopeptidase activity; heparin binding;calcium ion binding; growth factor activity; receptor binding; contributes toreceptor binging; thrombospondin receptor activity |
Products Types
◆ Recombinant Protein | ||
F2-955H | Recombinant Human F2 Protein, MYC/DDK-tagged | +Inquiry |
F2-907P | Recombinant Pig F2 Protein, His-tagged | +Inquiry |
F2-1356R | Recombinant Rhesus Macaque F2 Protein, His (Fc)-Avi-tagged | +Inquiry |
F2-995M | Recombinant Mouse F2 Protein, MYC/DDK-tagged | +Inquiry |
F2-1186M | Active Recombinant Mouse F2 protein(Met1-Gly618), His-tagged | +Inquiry |
◆ Native Protein | ||
Prothrombin-60H | Native Human Prothrombin Frag 2 | +Inquiry |
Thrombin-31M | Active Native Mouse Thrombin | +Inquiry |
F2-276B | Active Native Bovine α-Thrombin-FPRck (FPR-CMK*) | +Inquiry |
◆ Lysates | ||
F2-2124MCL | Recombinant Mouse F2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket