Native Mouse Coagulation Factor II


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Native Mouse Coagulation Factor II

F2 Related Products

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Cat. No. : F2-5287M
Product Overview : Mouse F2 isprepared from fresh frozen mouse plasma.
Description : F2is proteolytically cleaved to form thrombin in the first step of thecoagulation cascade, which ultimately results in the stemming of blood loss.F2 in turn acts as a serine protease that converts soluble fibrinogen intoinsoluble strands of fibrin, as well as catalyzing many other coagulation-relatedreactions.
Source : Mouse plasma
Form : Frozenliquid in 0.05 M HEPES Buffer + 0.1 M NaCl, pH 7.4.
Purity : > 95% by SDS-PAGEanalysis.
MolecularWeight : 72 kDa
EndotoxinLevel : < 0.1ng/μg of protein
Biological Activity : Activityis measured by clotting and/or chromogenic substrate assay, following conversionof prothrombinto thrombin.
Concentration : 5.0mg/ml
Storage : Store at -80°C. Stable for 3 years from delivery. Avoid repeated freeze-thaw cycles.
Pathways : BloodClotting Cascade; Cell surface interactions at the vascular wall; ClassA/1(Rhodopsin-like receptors); Common Pathway; Complement and CoaqulationCascades; Diabetes pathways; FOXA2 and FOXA3 transcription factor networks; ExtrinsicPathway; Formation of Fibrin Clot (Clotting Cascade); Hemostasis; IntrinsicPathway; Regulation of actin cytoskeleton; Selenium Pathway; SignalTransduction
Gene Name : F2coagulation factor II [ Mus musculus ]
Official Symbol : F2
Synonyms : F2; coagulation factor II;prothrombin; thrombin; Cf2; FII; Cf-2; OTTMUSP00000015068; EC;Prothrombin; Coagulation factor II; Thrombin light chain; Thrombin heavychain
Gene ID : 14061
mRNA Refseq : NM_010168
Protein Refseq : NP_034298
UniProt ID : P19221
Chromosome Location : 2
Function : peptidaseactivity;serine-typeendopeptidase activity; calcium ion binding; receptor binding; thrombospondinreceptor activity; catalytic activity; hydrolase activity; serine-type peptidaseactivity

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