"F2" Related Products

Native Mouse Coagulation Factor II

Cat. No.: F2-5287M
Product Overview: Mouse F2 isprepared from fresh frozen mouse plasma.
Description: F2is proteolytically cleaved to form thrombin in the first step of thecoagulation cascade, which ultimately results in the stemming of blood loss.F2 in turn acts as a serine protease that converts soluble fibrinogen intoinsoluble strands of fibrin, as well as catalyzing many other coagulation-relatedreactions.
Source: Mouse plasma
Form: Frozenliquid in 0.05 M HEPES Buffer + 0.1 M NaCl, pH 7.4.
Purity: > 95% by SDS-PAGEanalysis.
MolecularWeight: 72 kDa
EndotoxinLevel: < 0.1ng/μg of protein
Biological Activity: Activityis measured by clotting and/or chromogenic substrate assay, following conversionof prothrombinto thrombin.
Concentration: 5.0mg/ml
Storage: Store at -80°C. Stable for 3 years from delivery. Avoid repeated freeze-thaw cycles.
Pathways: BloodClotting Cascade; Cell surface interactions at the vascular wall; ClassA/1(Rhodopsin-like receptors); Common Pathway; Complement and CoaqulationCascades; Diabetes pathways; FOXA2 and FOXA3 transcription factor networks; ExtrinsicPathway; Formation of Fibrin Clot (Clotting Cascade); Hemostasis; IntrinsicPathway; Regulation of actin cytoskeleton; Selenium Pathway; SignalTransduction
Gene Name: F2coagulation factor II [ Mus musculus ]
Official Symbol: F2
Synonyms: F2; coagulation factor II;prothrombin; thrombin; Cf2; FII; Cf-2; OTTMUSP00000015068; EC 3.4.21.5;Prothrombin; Coagulation factor II; Thrombin light chain; Thrombin heavychain
Gene ID: 14061
mRNA Refseq: NM_010168
Protein Refseq: NP_034298
UniProt ID: P19221
Chromosome Location: 2
Function: peptidaseactivity;serine-typeendopeptidase activity; calcium ion binding; receptor binding; thrombospondinreceptor activity; catalytic activity; hydrolase activity; serine-type peptidaseactivity

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