Native Human Coagulation Factor IX


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Native Human Coagulation Factor IX

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Cat. No. : F9-671H
Product Overview : NativeHuman F9 is prepared from fresh frozen plasma by a combination ofconventional procedures and immunoaffinity chromatography.
Description : Human F9, activated by either the Contact or Tissue FactorPathway, is esponsible for the activation of Factor X to Xa.
Source : Human Plasma
Form : Frozenliquid in 0.02 M Tris-HCl Buffer + 0.1 M NaCl + 0.001 M Benzamidine, pH 7.4.
BiologicalActivity : Activity isdetermined via clotting assay.
Endotoxin Level : < 0.1 ng/ug ofprotein.
Concentration : 5.0 mg/ml
Molecular Weight : 56 kDa
Storage : Store at -80°C. Stable for 3 years fromdelivery. Avoid repeated freeze-thaw cycles.
Pathways : Blood Clotting Cascade; Complement andCoaqulation Cascades; Extrinsic Pathway; Formation of Fibrin Clot (ClottingCascade); Gamma-carboxylation of protein precursors; Gamma-carboxylation,transport, and amino-terminal cleavage of proteins; Hemostasis; IntrinsicPathway; Metabolism of proteins; Post-translational protein modification;Removal of aminoterminal propeptides from gamma-carboxylation proteins
PDB rendering basedon 1pfs. :

Gene Name : F9 coagulation factor IX [ Homo sapiens]
Official Symbol : F9
Synonyms : F9; coagulation factor IX;FIX;P19; PTC; HEMB; MGC129641; MGC129642; F9p22; factor9; factor IX F9; serine protease; Christmas factor; OTTHUMP00000024154;plasma thromboplastic component; EC; EC 3.4.21; Coagulation factorIX; Plasma thromboplastic component; Coagulation factor IX light chain; Coagulationfactor IX heavy chain; Factor IX; hemophilia B
Gene ID : 2158
mRNA Refseq : NM_000133
Protein Refseq : NP_000124
MIM : 300746
UniProt ID : P00740
Chromosome Location : Xq27.1-q27.2
Function : peptidase activity; calciumion binding; serine-typeendopeptidase activity

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