"Fgf7" Related Products


Recombinant Mouse Fibroblast Growth Factor 7

Cat. No.: Fgf7-649M
Product Overview: Recombinant Mouse Fibroblast Growth Factor-7 is a single, non-glycosylated polypeptide chain containing 164 amino acids.
Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
Source: E. coli
Molecular Mass: 18.9 kDa
Formulation: Lyophilized from a 0.2µm filtered solution in 20 mM PBS, pH 8.0 + 1M NaCl.
Purity: >96% as determined by SDS­PAGE and HPLC analyses.
Endotoxin Level: <0.1 ng/µg of protein
Biological Activity: The biological activity was determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing KGF receptors yielding an ED50 < 10 ng/ml.
Reconstitution: Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1 to 1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at -20 °C to -80 °C. Further dilutions should be made in appropriate buffered solutions.
Storage: Store at -20 °C, preferably desiccated. Upon reconstitution, the preparation is stable for up to 1 week at 2-4 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -80 °C. Avoid repeated freeze/thaw cycles.
OfficialSymbol: Fgf7
Gene Name: Fgf7 fibroblast growth factor 7 [ Mus musculus ]
Synonyms: Kgf; fibroblast growth factor 7; FGF-7; HBGF-7; Keratinocyte growth factor; heparin-binding growth factor 7; FGF7; KGF
Gene ID: 14178
mRNA Refseq: NM_008008
Protein Refseq: NP_032034
UniProt ID: P36363
Chromosome Location: 2; 2 F-G
Pathway: Activated point mutants of FGFR2; Adaptive Immune System; Constitutive PI3K/AKT Signaling in Cancer
Function: chemoattractant activity; growth factor activity; heparin binding; protein binding; type 2 fibroblast growth factor receptor binding

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