"ANXA1" Related Products


Recombinant Human Annexin A1, His-tagged

Cat. No.: ANXA1-5257H
Product Overview: Recombinanthuman ANXA1 was expressed in E.coli with an N-terminal Histag.
Description: AnnexinI (ANXA1), otherwise known as Lipocortin 1, is a calcium-dependentphospholipid-binding protein and member of the annexin family, preferentiallyexpressed on the cytosolic face of the plasma membrane, which acts as aninhibitor of phospholipase A2, and may exhibit anti-inflammatory activity.Increased expression of the ANXA1 gene in hairy cell leukaemia, can be usedin immunohistochemistry as a highly-sensitive diagnostic marker.
Form: Purified recombinantprotein-liquid.
Application: ELISA; West Blotting
Preparation: Purified recombinant6x His-tagged ANXA1 expressed in E.coli.
Buffer Solution: 20mM, Tris-HCl 0.5MNaCl, 100mM Imidazole, 1mM Beta-mercaptoethanol, pH8.0.
Molecular Weight: 41.4 kD (368 aminoacid residues with tag).
Concentration: 0.5mg/ml
Storage: Store at -70oC.Storage in frost-free freezers is not recommended. This product should bestored undiluted. Avoid repeated freezing and thawing as this may denaturethe antibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.
Pathways: Class A/1(Rhodopsin-like receptors); Formyl peptide receptors bind formyl peptides andmany other ligands; G alpha (i) signalling events; G alpha (q) signallingevents; GPCR downstream signaling; GPCR ligand binding; Peptideligand-binding receptors; Prostaglandin Synthesis and Regulation; Signalingby GPCR
Gene Name: ANXA1 annexin A1 [ Homosapiens ]
Official Symbol: ANXA1
Synonyms: ANXA1;annexin A1; ANX1;LPC1; annexin A1; p35; annexin-1; calpactin-2; calpactin II; lipocortin I;chromobindin-9; OTTHUMP00000021474; OTTHUMP00000021475; annexin I (lipocortinI); phospholipase A2 inhibitory protein
Gene ID: 301
mRNA Refseq: NM_000700
Protein Refseq: NP_000691
MIM: 151690
UniProt ID: P04083
Chromosome Location: 9q21.13
Function: calcium ion binding;calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity;phospholipase inhibitor activity; phospholipid binding; protein binding;protein binding; protein homodimerization activity; receptor binding;single-stranded DNA binding; structural molecule activity; single-strandedRNA binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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