Recombinant Human Annexin A1, His-tagged


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Recombinant Human Annexin A1, His-tagged

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Cat. No. : ANXA1-5257H
Product Overview : Recombinanthuman ANXA1 was expressed in E.coli with an N-terminal Histag.
Description : AnnexinI (ANXA1), otherwise known as Lipocortin 1, is a calcium-dependentphospholipid-binding protein and member of the annexin family, preferentiallyexpressed on the cytosolic face of the plasma membrane, which acts as aninhibitor of phospholipase A2, and may exhibit anti-inflammatory activity.Increased expression of the ANXA1 gene in hairy cell leukaemia, can be usedin immunohistochemistry as a highly-sensitive diagnostic marker.
Form : Purified recombinantprotein-liquid.
Application : ELISA; West Blotting
Preparation : Purified recombinant6x His-tagged ANXA1 expressed in E.coli.
Buffer Solution : 20mM, Tris-HCl 0.5MNaCl, 100mM Imidazole, 1mM Beta-mercaptoethanol, pH8.0.
Molecular Weight : 41.4 kD (368 aminoacid residues with tag).
Concentration : 0.5mg/ml
Storage : Store at -70oC.Storage in frost-free freezers is not recommended. This product should bestored undiluted. Avoid repeated freezing and thawing as this may denaturethe antibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.
Pathways : Class A/1(Rhodopsin-like receptors); Formyl peptide receptors bind formyl peptides andmany other ligands; G alpha (i) signalling events; G alpha (q) signallingevents; GPCR downstream signaling; GPCR ligand binding; Peptideligand-binding receptors; Prostaglandin Synthesis and Regulation; Signalingby GPCR
PDB rendering based on 1ain. :

Gene Name : ANXA1 annexin A1 [ Homosapiens ]
Official Symbol : ANXA1
Synonyms : ANXA1;annexin A1; ANX1;LPC1; annexin A1; p35; annexin-1; calpactin-2; calpactin II; lipocortin I;chromobindin-9; OTTHUMP00000021474; OTTHUMP00000021475; annexin I (lipocortinI); phospholipase A2 inhibitory protein
Gene ID : 301
mRNA Refseq : NM_000700
Protein Refseq : NP_000691
MIM : 151690
UniProt ID : P04083
Chromosome Location : 9q21.13
Function : calcium ion binding;calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity;phospholipase inhibitor activity; phospholipid binding; protein binding;protein binding; protein homodimerization activity; receptor binding;single-stranded DNA binding; structural molecule activity; single-strandedRNA binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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