Cat. No.:	IL1B-589C
Product Overview:	Recombinant Chicken IL1Bis a 23 kDa protein and was expressed in E. coli.
Description:	IL1B is apro-inflammatory cytokine secreted by many different cell types which actsupon a wide range of target cells, resulting in a diverse range of effects.The biological properties of IL1B include the induction of B cellproliferation, stimulation of T cell proliferation in conjunction with IL-2and the production of collagenase and prostaglandin by fibroblasts. IL1B isalso responsible for triggering the acute-phase response in the liver, and isinvolved in both cytokine network and vascular endothelium activation.
Form:	Purified His-taggedrecombinant protein expressed in E.coli - liquid.
Application:	Functional Assays;In vitro Assay
Preparation:	Recombinant protein prepared from E.coli.
Molecular Weight:	approximately 23kD
Purity:	> 85% by Nichelate Chromatography
Concentration:	250 ug/ml
Storage:	Store at -20oC only. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.

Gene Name:	IL1B interleukin 1, beta [ Gallusgallus ]
Official Symbol:	IL1B
Synonyms:	IL1B; interleukin 1,beta; IL1beta; IL-1BETA; interleukin-1 beta; IL-1 beta
Gene ID:	395196
mRNA Refseq:	NM_204524
Protein Refseq:	NP_989855
Chromosome Location:	22
Pathway:	Apoptosis;Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Herpessimplex infection; Influenza A; MAPK signaling pathway; Myometrial Relaxationand Contraction Pathways; NOD-like receptor signaling pathway; Salmonellainfection; Toll-like receptor signaling pathway
Function:	cytokineactivity; interleukin-1 receptor binding; protein domain specific binding

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