Recombinant Human Retinol Dehydrogenase 12 (all-trans/9-cis/11-cis), His-tagged
Cat.No. : | RDH12-1371H |
Product Overview : | Recombinanthuman RDH12protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | RDH12-1371H |
Description : | RDH12 belongs to theshort-chain dehydrogenases /reductases (SDR) family. RDH12 is expressed,mostly in eye, kidney, brain, skeletal muscle and stomach. It is anNADPH-dependent retinal reductase whose highest activity is toward 9-cis andall-trans-retinol. RDH12 also plays a role in the metabolism of short-chainaldehydes but does not exhibit steroid dehydrogenase activity. |
Form : | Liquid. In 20 mMTris-HCl buffer (pH 8.0) containing 2 mM DTT, 40% glycerol, 0.2M NaCl. |
Molecular Weight : | 33.5 kDa(303 aa), confirmed by MALDI-TOF. |
Purity : | > 90%by SDS-PAGE |
Concentration : | 0.25mg/ml(determined by Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSHMGKVVV ITGANTGIGK ETARELASRG ARVYIACRDVLKGESAASEI RVDTKNSQVL VRKLDLSDTK SIRAFAEGFLAEEKQLHILI NNAGVMMCPY SKTADGFETH LGVNHLGHFL LTYLLLERLK VSAPARVVNV SSVAHHIGKIPFHDLQSEKR YSRGFAYCHS KLANVLFTRE LAKRLQGTGV TTYAVHPGVV RSELVRHSSL LCLLWRLFSPFVKTAREGAQ TSLHCALAEG LEPLSGKYFS DCKRTWVSPRARNNKTAERL WNVSCELLGI RWE |
Storage : | Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Metabolicpathways; Retinol metabolism; Visual signal transduction; Vitamin A andcarotenoid metabolism |
Gene Name : | RDH12 retinol dehydrogenase 12(all-trans/9-cis/11-cis) [ Homo sapiens ] |
Official Symbol : | RDH12 |
Synonyms : | RDH12; retinoldehydrogenase 12 (all-trans/9-cis/11-cis); LCA3; LCA13; SDR7C2;FLJ30273; retinoldehydrogenase 12; all-trans and 9-cis retinol dehydrogenase; retinoldehydrogenase 12, all-trans and 9-cis; short chain dehydrogenase/reductasefamily 7C, member 2 |
Gene ID : | 145226 |
mRNA Refseq : | NM_152443 |
Protein Refseq : | NP_689656 |
MIM : | 608830 |
UniProt ID : | Q96NR8 |
Chromosome Location : | 14q24.1 |
Function : | binding;oxidoreductase activity; retinol dehydrogenase activity |
Products Types
◆ Recombinant Protein | ||
RDH12-7508M | Recombinant Mouse RDH12 Protein, His (Fc)-Avi-tagged | +Inquiry |
RDH12-3655R | Recombinant Rhesus Macaque RDH12 Protein, His (Fc)-Avi-tagged | +Inquiry |
RDH12-14047M | Recombinant Mouse RDH12 Protein | +Inquiry |
RDH12-3838R | Recombinant Rhesus monkey RDH12 Protein, His-tagged | +Inquiry |
RDH12-31307TH | Recombinant Human RDH12, His-tagged | +Inquiry |
◆ Lysates | ||
RDH12-2437HCL | Recombinant Human RDH12 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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