Recombinant Human Tumor Necrosis Factor
Cat.No. : | TNF-378H |
Product Overview : | Recombinant human TNFalpha is expressed in human 293 cells and has been shown by gel filtration tobe predominantly a non-covalently linked homotrimer, with a molecular mass of51 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TNF-378H |
Description : | Tumor necrosisfactor-alpha is the best-known member of this class, and sometimes referredto when the term tumor necrosis factor is used. TNF is a monocyte-derivedcytotoxin that has been implicated in tumour regression, septic shock andcachexia. |
Source : | HEK 293 cells |
Species : | Human |
Purity : | >95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue. |
Molecular Mass : | 17 kDa,non-disulfided bonded homotrimer, glycosylate. |
Endotoxin Level : | Endotoxin Free <1EU/μg |
Biological Activity : | 0.05 to 0.5 ng/mL ED50 |
Specific Activity : | The specificactivity was determined by the dose-dependent cytotoxity of the TNF alphasensitive cell line L-929 in the presence of Actinomycin D. |
OfficialSymbol : | TNF |
Pathways : | Adipocytokinesignaling pathway; Adipogenesis; African trypanosomiasis; Allograftrejection; Alzheimer" s disease; Amoebiasis; Amyotrophic lateral sclerosis(ALS); Angiopoietin receptor Tie2-mediated signaling; Antigen processing andpresentation; Apoptosis; Asthma; Calcineurin-regulated NFAT-dependenttranscription in lymphocytes; Canonical NF-kappaB pathway; Caspase cascade inapoptosis; Cellular roles of Anthrax toxin; Ceramide signaling pathway |
Gene Name : | TNF tumor necrosis factor [ Homosapiens ] |
Synonyms : | TNF;tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNF-a; cachectin;APC1 protein; OTTHUMP00000029281; TNF, monocyte-derived; TNF,macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha;tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member2; Tumornecrosis factor; Cachectin |
Gene ID : | 7124 |
mRNA Refseq : | NM_000594 |
Protein Refseq : | NP_000585 |
MIM : | 191160 |
UniProt ID : | P01375 |
Chromosome Location : | 6p21.3 |
Function : | cytokine activity; identicalprotein binding; protease binding; protein binding; transcription regulatoryregion DNA binding; tumor necrosis factor receptor binding |
Products Types
◆ Recombinant Protein | ||
TNF-63H | Active Recombinant Human TNF Protein, FLAG-tagged | +Inquiry |
Tnf-305T | Active Recombinant Mouse Tnf Protein (163 aa), His-tagged | +Inquiry |
TNF-20B | Active Recombinant Bovine TNF Protein | +Inquiry |
TNF-51H | Recombinant Human TNF Protein | +Inquiry |
TNF-716B | Active Recombinant Bovine TNF Protein | +Inquiry |
◆ Lysates | ||
TNF-897HCL | Recombinant Human TNF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All TNF Products
Required fields are marked with *
My Review for All TNF Products
Required fields are marked with *
0
Inquiry Basket