Recombinant Human Fas-activated Serine/Threonine Kinase, T7-tagged

• Cat.No.: FASTK-824H
• Product Overview: Recombinant Human FASTK protein was expressed in E.coliwith T7-tag at the N-terminus. The molecular weight is 61104 Da

Specification

• Cat. No.: FASTK-824H
• Description: FASTK Fas-activated serine/threonine kinase encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
• Sequences of amino acids: 1-471 aa
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT
• Purity: 95%

Gene Information

• Gene Name: FASTK Fas-activated serine/threonine kinase [Homo sapiens]
• Synonyms: FAST; FAST kinase; EC 2.7.11.8; serine/threonine kinase; FASTK OTTHUMP00000213278; fas-activated; OTTHUMP00000213305
• Gene ID: 10922
• mRNA Refseq: NM_006712
• Protein Refseq: NP_006703
• MIM: 606965
• UniProt ID: Q14296
• Chromosome Location: 7q35
• Function: ATP binding;Fas-activated serine/threonine kinase activity;nucleotide binding;protein binding;protein serine/threonine kinase activity;transferase activity