Native Bovine Vitronectin

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Cat. No. :	VTN-384B
Product Overview :	Native bovinemultimeric Vitronectin prepared from fresh bovine plasma using urea as adenaturant.
Description :	The protein encodedby this gene is a member of the pexin family. Vitronectin is an abundantglycoprotein found in serum and the extracellular matrix and promotes celladhesion and spreading, inhibits the membrane-damaging effect of the terminalcytolytic complement pathway, and binds to several serpin serine protease inhibitors.
Source :	Bovine plasma
Species :	Bovine
Form :	Liquid in 0.1 Msodium phosphate + 0.15 M NaCl, pH 7.4.
Molecular Weight :	68.0 kDa
Concentration :	4.0 mg/ml
Storage :	Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol :	VTN
Pathways :	ECM-receptorinteraction; Focal adhesion; Integrin cell surface interactions; SignalTransduction
The SMB domain(yellow) in complex with PAI-1 :

Gene Name :	VTN vitronectin [ Bostaurus ]
Synonyms :	VTN; vitronectin;vitronectin (serum spreading factor, somatomedin B, complement S-protein); Uncharacterized protein; Vitronectin
Gene ID :	507525
mRNA Refseq :	NM_001035050
Protein Refseq :	NP_001030222
UniProt ID :	Q3ZBS7
Chromosome Location :	19
Function :	extracellular matrixbinding; integrin binding; polysaccharide binding; scavenger receptoractivity