"GCA" Related Products


Recombinant Human GCA grancalcin, EF-hand Calcium Binding Protein, His-tagged

Cat. No.: GCA-2921H
Product Overview: Recombinant Human GCA protein was expressed in E.coli with His-tag at the N-terminus. The molecular weight is 24010 Da(217 aa).
Description: Grancalcin is a protein that in humans is encoded by the GCA gene. grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
Sequences of amino acids: 1-217 aa
Formulation: 10 mM Tris. pH 8.0. 0.002% NaN3. 3mM NaCl. 2.5mM Imidazole.
Purity: 95%
Gene Name: GCA grancalcin, EF-hand calcium binding protein [ Homo sapiens ]
Synonyms: GCL; grancalcin; OTTHUMP00000204639; OTTHUMP00000204640; grancalcin, penta-EF-hand protein; grancalcin, EF-hand calcium-binding protein
Gene ID: 25801
mRNA Refseq: NM_012198
Protein Refseq: NP_036330
MIM: 607030
UniProt ID: P28676
Chromosome Location: 2q37.1
Pathway: Insulin signaling pathway; mTOR signaling pathway
Function: calcium ion binding; protein homodimerization activity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.