Recombinant Human GCA, His-tagged
Cat.No. : | GCA-26242TH |
Product Overview : | Recombinant full length Human Grancalcin with an N terminal His tag; 237 amino acids with tag, Predicted MWt 26.1 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. |
Protein length : | 217 amino acids |
Conjugation : | HIS |
Molecular Weight : | 26.100kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMAYPG YGGGFGNFSIQVPGMQMGQPVPETG PAILLDGYSGPAYSDTYSSAGDSVY TYFSAVAGQDGEVDAEELQRCLTQS GINGTYSPFSLETCRIMIAMLDRDH TGKMGFNAFKELWAALNAWKENFMT VDQDGSGTVEHHELRQAIGLMGYRL SPQTLTTIVKRYSKNGRIFFDDYVA CCVKLRALTDFFRKRDHLQQGSANF IYDDFLQGTMAI |
Gene Name : | GCA grancalcin, EF-hand calcium binding protein [ Homo sapiens ] |
Official Symbol : | GCA |
Synonyms : | GCA; grancalcin, EF-hand calcium binding protein; grancalcin, EF hand calcium binding protein; grancalcin; GCL; |
Gene ID : | 25801 |
mRNA Refseq : | NM_012198 |
Protein Refseq : | NP_036330 |
MIM : | 607030 |
Uniprot ID : | P28676 |
Chromosome Location : | 2p14-q14.3 |
Function : | calcium ion binding; protein homodimerization activity; |
Products Types
◆ Recombinant Protein | ||
GCA-1640R | Recombinant Rhesus Macaque GCA Protein, His (Fc)-Avi-tagged | +Inquiry |
GCA-1316H | Recombinant Human GCA Protein | +Inquiry |
GCA-4787H | Recombinant Human GCA Protein, GST-tagged | +Inquiry |
Gca-3170M | Recombinant Mouse Gca Protein, Myc/DDK-tagged | +Inquiry |
GCA-4382H | Recombinant Human Grancalcin, EF-hand Calcium Binding Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
GCA-2H | Native Human Gastrointestinal Cancer Antigen | +Inquiry |
◆ Lysates | ||
GCA-5994HCL | Recombinant Human GCA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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