"TP63" Related Products


Recombinant Human Tumor Protein P63

Cat. No. : TP63-700H
Product Overview : Recombinant human TP63was expressed in E. coli.
Description : The TP63 gene, ahomologue of the tumor-suppressor p53, is highly expressed in the basal orprogenitor layers of many epithelial tissues. TP63 shows remarkablestructural similarity to p53 and to the related p73 gene. Unlike p53, the TP63gene encodes multiple isotypes with remarkably divergent abilities totransactivate p53 reporter genes and induce apoptosis.
Source : E. coli
Species : Human
Form : Recombinant Humanp63 at 100 µg/ml in 50 mM Tris-Acetate, pH 7.5 +1 mM EDTA + 20% Glycerol.
Applications : ELISA; InhibitionAssays; Western Blotting
Storage : Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stablefor 12 months.
OfficialSymbol : TP63
Gene Name : TP63 tumor protein p63 [ Homosapiens ]
Synonyms : TP63; tumor proteinp63; AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4;TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B); CUSP; OTTHUMP00000209732;OTTHUMP00000209733; OTTHUMP00000209734; OTTHUMP00000209735;OTTHUMP00000209737; OTTHUMP00000209738; OTTHUMP00000209739; OTTHUMP00000209740;OTTHUMP00000209741; OTTHUMP00000209742; OTTHUMP00000209743;OTTHUMP00000209744; transformation-related protein 63; tumor proteinp53-competing protein; amplified in squamous cell carcinoma; chroniculcerative stomatitis protein; keratinocyte transcription factor KET; tumorprotein p63 deltaN isoform delta
Gene ID : 8626
mRNA Refseq : NM_003722
Protein Refseq : NP_003713
MIM : 603273
UniProt ID : Q9H3D4
Chromosome Location : 3q28
Pathway : Apoptosis; Directp53 effectors; TP53 network
Function : DNA binding;chromatin binding; damaged DNA binding; double-stranded DNA binding;identical protein binding; metal ion binding; p53 binding; protein binding;sequence-specific DNA binding; sequence-specific DNA binding transcriptionfactor activity; transcription regulatory region DNA binding

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