Recombinant Human Vascular Endothelial Growth Factor A, His-tagged

• Cat.No.: VEGFA-713H
• Product Overview: Recombinant HumanVEGF with His tag is a non-glycosylated, monomeric polypeptide chaincontaining a fragment of 165 amino acids (aa 5-169) and an N-terminal Histag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 5-169 a.a.
• Description: VEGFA circulatesmore freely than other VEGF forms, which bind more tightly with vascularheparin sulfates. A vascular endothelial growth factor (VEGF) mRNA speciescontaining exons 1–6 and 8 of the VEGF gene was found to be expressed as amajor VEGF mRNA form in several cell lines derived from carcinomas of thefemale reproductive system.
• Form: Sterile filteredliquid in 20 mM Tris HCl, pH 8.0 + 50% glycerol + 0.05 mM DTT
• Molecule weight: 23.6 kDa
• Concentration: 0.053 mg/ml
• Purity: > 95.0% asdetermined by RP-HPLC and SDS-PAGE analyses
• Endotoxin Level: < 0.1 ng/µg ofVEGF
• Storage: Stable for 4 weeksat 2-4°C. For long term storage, aliquot and store at -20°C. Avoid repeatedfreeze-thaw cycles.
• OfficialSymbol: VEGFA

Gene Information

• Gene Name: VEGFA vascular endothelialgrowth factor A [ Homo sapiens ]
• Synonyms: VEGFA; vascularendothelial growth factor A; VPF; VEGF; MVCD1; OTTHUMP00000016487;OTTHUMP00000016488; OTTHUMP00000165985; OTTHUMP00000165986;OTTHUMP00000165987; OTTHUMP00000224107; OTTHUMP00000224108;OTTHUMP00000224109; OTTHUMP00000224153; OTTHUMP00000224154;OTTHUMP00000224423; OTTHUMP00000224424; OTTHUMP00000224425;OTTHUMP00000224426; OTTHUMP00000224427; OTTHUMP00000224428;OTTHUMP00000224429; OTTHUMP00000224430; vascular permeability factor
• Gene ID: 7422
• mRNA Refseq: NM_003376
• Protein Refseq: NP_003367
• MIM: 192240
• UniProt ID: P15692
• Chromosome Location: 6p12
• Pathway: Bladder cancer;Cytokine-cytokine receptor interaction; Endochondral Ossification; Focaladhesion; Glypican 1 network; HIF-1-alpha transcription factor network; IdSignaling Pathway; Neurophilin interactions with VEGF and VEGFR; Pancreaticcancer; Renal cell carcinoma; Signal Transduction; Signaling events mediatedby VEGFR1 and VEGFR2; VEGF ligand-receptor interactions; VEGFR1 specificsignals; mTOR signaling pathway
• Function: cell surfacebinding; chemoattractant activity; cytokine activity; extracellular matrixbinding; fibronectin binding; growth factor activity; heparin binding;platelet-derived growth factor receptor binding; protein binding; proteinheterodimerization activity; vascular endothelial growth factor receptor 1binding; vascular endothelial growth factor receptor 2 binding; vascularendothelial growth factor receptor binding