Recombinant Human Keratin 14

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Recombinant Human Keratin 14

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Cat. No. : KRT14-374H
Product Overview : Recombinant humanKRT14 is a single, non-glycosylated polypeptide chain.
Description : KRT14, type I cytoskeletal 14 also known ascytokeratin-14 (CK-14) or keratin-14 (K14) is a protein that in humans isencoded by the KRT14 gene. Keratin 14 is a type I keratin. It is usuallyfound as a heterotetramer with two keratin 5 molecules, a type II keratin.Together they form the cytoskeleton of epithelial cells.
Source : E. coli
Species : Human
Form : Lyophilized from asterile filtered solution containing 30 mM Tris-HCl, pH 8.0 + 9.5 M urea + 2mM EDTA + 10 mM methylammonium chloride.
Molecular Weight : 51.53 kDa
Purity : > 95% asdetermined by SDS-PAGE and RP-HPLC analyses.
Endotoxin Level : < 0.1 ng/µg ofKRT14.
Reconstitution : Centrifuge vialprior to opening. First add sterile distilled water to the vial to fully solubilizethe protein to a concentration not less than 100 µg/ml. After complete solubilizationof the protein, it can be further diluted to other aqueous solutions.
Storage : Store lyophilizedprotein at -20°C to -80°C. Reconstituted protein is stable for 1 week at 2-4°C.For long term storage, aliquot and store at -20°C to -80°C with a carrierprotein (0.1% HSA or BSA) as a stabilizer. Please note that the addition ofany carrier protein into this product may produce unwanted endotoxin. Thisdepends upon the particular application employed. Avoid repeated freeze-thawcycles.
OfficialSymbol : KRT14
Gene Name : KRT14 keratin 14 [ Homosapiens ]
Synonyms : KRT14; keratin 14;K14; NFJ; CK14; EBS3; EBS4; keratin, type I cytoskeletal 14; CK-14;keratin-14; cytokeratin 14; Cytokeratin-14; cytokeratin-14; Keratin-14;OTTHUMP00000164624; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara,Koebner)
Gene ID : 3861
mRNA Refseq : NM_000526
Protein Refseq : NP_000517
MIM : 148066
UniProt ID : P02533
Chromosome Location : 17q12-q21
Pathway : Glucocorticoidreceptor regulatory network
Function : protein binding;structural constituent of cytoskeleton
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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