Recombinant Human Distal-less Homeobox 4

• Cat.No.: DLX4-5388H
• Product Overview: Recombinant Human DLX4contains amino acids 103-168.

Specification

• Cat. No.: DLX4-5388H
• Description: Homeobox protein DLX4 is a protein that in humans is encoded by the DLX4gene. Many vertebrate homeo box-containing genes have been identified on thebasis of their sequence similarity with Drosophila developmental genes.Members of the Dlx gene family contain a homeobox that is related to that ofDistal-less (Dll), a gene expressed in the head and limbs of the developingfruit fly. The Distal-less (Dlx) family of genes comprises at least 6different members, DLX1-DLX6. The DLX proteins are postulated to play a rolein forebrain and craniofacial development. Three transcript variants havebeen described for this gene, however, the full length nature of one varianthas not been described. Studies of the two splice variants revealed that oneencoded isoform functions as a repressor of the beta-globin gene while theother isoform lacks that function.
• Source: E. coli
• Species: Human
• Form: Sterile filteredliquid in 50 mM Tris-Acetate, pH 7.5 + 1 mM EDTA + 20% glycerol.
• Molecular Weight: 35 kDa
• Concentration: 0.1 mg/ml
• Applications: Western Blot; ELISA;Inhibition Assays; The optimal concentration should be determined by the userfor each specific application.
• Storage: Stable for 1 year at-20°C to -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: DLX4

Gene Information

• Gene Name: DLX4 distal-less homeobox 4 [ Homosapiens ]
• Synonyms: DLX4; distal-lesshomeobox 4; BP1; DLX7; DLX8; DLX9; homeobox protein DLX-4; beta protein 1;Beta protein 1; OTTHUMP00000220790; OTTHUMP00000220791; homeobox proteinDLX-7; homeobox protein DLX-8; distal-less homeo box 7; distal-less homeo box9; Homeobox protein DLX-7
• Gene ID: 1748
• mRNA Refseq: NM_001934
• Protein Refseq: NP_001925
• MIM: 601911
• UniProt ID: Q92988
• Chromosome Location: 17q21.33
• Function: protein binding;sequence-specific DNA binding; sequence-specific DNA binding transcriptionfactor activity; transcription regulatory region sequence-specific DNAbinding