"EPHB1" Related Products


Recombinant Human EPH Receptor B1, GST-tagged

Cat. No. : EPHB1-1213H
Product Overview : Recombinant humanEPHB1 catalytic domain (aa 612-887) with GST tag. No special measures weretaken to activate this kinase.
Description : EPHB1 is a protein that in humans is encoded by theEPHB1 gene. Ephrin receptors and their ligands,the ephrins, mediate numerous developmental processes, particularly in thenervous system. Based on their structures and sequence relationships, ephrinsare divided into the ephrin-A (EFNA) class, which are anchored to themembrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB)class, which are transmembrane proteins.
Source : Insect cells
Species : Human
Form : Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
Molecular Weight : 60.3 kDa
Concentration : 0.49 mg/ml
Purity : ≥ 90% as determinedby SDS-PAGE analysis.
Specific Activity : 645 nmole ofphosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg of totalprotein at 30°C.Activity determined at a final protein concentration of 2 μg/ml.
Storage : Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : EPHB1
PDBrendering based on 2djs. :

Gene Name : EPHB1 EPH receptor B1 [ Homosapiens ]
Synonyms : EPHB1; EPH receptorB1; ELK;NET; Hek6; EPHT2; FLJ37986; ephrin type-B receptor 1; EK6; EPH-like kinase 6;OTTHUMP00000216707; OTTHUMP00000216708; eph tyrosine kinase 2; soluble EPHB1variant 1; tyrosine-protein kinase receptor EPH-2; neuronally-expressedEPH-related tyrosine kinase
Gene ID : 2047
mRNA Refseq : NM_004441
Protein Refseq : NP_004432
MIM : 600600
UniProt ID : P54762
Chromosome Location : 3q21-q23
Pathway : Axon guidance; EPHBforward signaling; Ephrin B reverse signaling; EphrinB-EPHB pathway
Function : ATP binding; axonguidance receptor activity; nucleotide binding; protein binding; receptoractivity; transmembrane-ephrin receptor activity

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