Recombinant Mouse Kit Ligand, His-tagged
Cat.No. : | Kitl-1243M |
Product Overview : | Recombinant mouseKitl contains 175 amino acids and a 13 amino acid Histidine-based tag for atotal length of 188 amino acids and its predicted molecular weight of therecombinant Kitl with His tag polypeptide is 24, 23, and 21 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Kitl-1243M |
Description : | Kitl (also known asSCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kitreceptor (CD117). Kitl can exist both as a transmembrane protein and asoluble protein. This cytokine plays an important role in hematopoiesis(formation of blood cells), spermatogenesis, and melanogenesis. |
Source : | Hordeum vulgare(barley grain) |
Species : | Human |
Form : | Lyophilized from a0.2 µm sterile filtered solution in 30 mM sodium acetate + 0.7 M NaCl, pH 4.5 |
Purity : | > 98% asdetermined by SDS-PAGE analysis |
Endotoxin Level : | < 0.005 ng/µg ofSCF |
Biological Activity : | Determined bymeasuring the dose dependent effect of mouse SCF on proliferation of thefactor-dependent human erythroleukemic cell line TF-1. The ED50 range is8.4-12.8 ng/ml. |
Reconstitution : | Centrifuge vialprior to opening. Add sterile PBS to the vial to fully solubilize the proteinto a concentration not less than 50 µg/ml. |
Storage : | Store lyophilizedprotein at -20°C and reconstituted protein in working aliquots at -20°C witha carrier protein (0.1% HSA or BSA) as a stabilizer for long term storage. Pleasenote that the addition of any carrier protein into this product may produce unwantedendotoxin. This depends upon the particular application employed. Avoidrepeated freeze-thaw cycles. |
OfficialSymbol : | Kitl |
Gene Name : | Kitl kit ligand [ Musmusculus ] |
Synonyms : | Kitl; kit ligand;Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; Kitlg; contrasted; kit ligand; cloudgray; C-kit ligand; Steel factor; grizzle-belly; stem cell factor;OTTMUSP00000022753; OTTMUSP00000022754; mast cell growth factor;hematopoietic growth factor KL |
Gene ID : | 17311 |
mRNA Refseq : | NM_013598 |
Protein Refseq : | NP_038626 |
UniProt ID : | P20826 |
Chromosome Location : | 10 D1; 10 57.0 cM |
Pathway : | Cytokine-cytokinereceptor interaction; Hematopoietic cell lineage; Kit Receptor SignalingPathway; Melanogenesis; Pathways in cancer; Regulation of KIT signaling;Signal Transduction; Signaling by SCF-KIT |
Function : | cytokine activity;growth factor activity; protein binding; stem cell factor receptor binding |
Products Types
◆ Recombinant Protein | ||
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KITLG-19H | Active Recombinant Human KITLG Protein, Pre-aliquoted | +Inquiry |
Kitl-1713M | Recombinant Mouse Kitl Protein, His-tagged | +Inquiry |
Kitlg-200R | Recombinant Rat Kitlg Protein | +Inquiry |
KITLG-152K | Active Recombinant Human KITLG Protein (165 aa) | +Inquiry |
◆ Lysates | ||
KITLG-583MCL | Recombinant Mouse KITLG cell lysate | +Inquiry |
KITLG-571HCL | Recombinant Human KITLG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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