"KITLG" Related Products

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Recombinant Human KIT Ligand

Cat. No. : KITLG-1245H
Product Overview : Recombinant Human KITLGis expressed in human 293 cells as a monomeric glycoprotein with an apparent molecularmass of 35 to 45 kDa.
Description : KITLG (also knownas SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to thec-Kit receptor (CD117). KITLG can exist both as a transmembrane protein and asoluble protein. This cytokine plays an important role in hematopoiesis(formation of blood cells), spermatogenesis, and melanogenesis.
Source : HEK 293 cells
Species : Human
MolecularWeight : 35 to 45 kDa,monomer, glycosylated
Purity : >95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue.
Endotoxin Level : Endotoxin Free<1 EU/µg
Biological Activity : 5 to 25 ng/mL ED50
Specific Activity : The specificactivity was determined by the dose-dependent stimulation of the proliferationof human TF-1 cells (human erythroleukemic indicator cell line).
OfficialSymbol : KITLG
PDB rendering basedon 1exz. :

Gene Name : KITLG KIT ligand [ Homosapiens ]
Synonyms : KITLG; KIT ligand;SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7; kit-ligand; DKFZp686F2250; kit ligand;c-Kit ligand; steel factor; stem cell factor; OTTHUMP00000242388;OTTHUMP00000242389; OTTHUMP00000242390; mast cell growth factor; familialprogressive hyperpigmentation 2
Gene ID : 4254
mRNA Refseq : NM_000899
Protein Refseq : NP_000890
MIM : 184745
UniProt ID : P21583
Chromosome Location : 12q22
Pathway : C-MYB transcriptionfactor network; Cytokine-cytokine receptor interaction; Hematopoietic celllineage; Kit Receptor Signaling Pathway; Melanogenesis; Pathways in cancer;Regulation of KIT signaling; Signal Transduction; Signaling by SCF-KIT;Signaling events mediated by Stem cell factor receptor (c-Kit)
Function : cytokine activity;growth factor activity; protein binding; stem cell factor receptor binding

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