Recombinant Human p21 Protein (Cdc42/Rac)-Activated Kinase 6, His-tagged
| Cat.No. : |
PAK6-1284H |
| Product Overview : |
Recombinant humanfull length PAK6 is a serine/threonine kinase expressed in the testis andprostate. Itassociates with both the estrogen and androgen receptors. No special measureswere taken to activate this kinase. Itsmolecular weight is 79900 Dalton. |
- Specification
- Gene Information
- Related Products
| Cat. No. : |
PAK6-1284H |
| Description : |
Serine/threonine-proteinkinase PAK6 is an enzyme that in humans is encoded by the PAK6 gene. Thisgene encodes a protein that shares a high degree of sequence similarity withp21-activated kinase (PAK) family members. The proteins of this family areRac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by ahighly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domainand a carboxyl-terminal kinase domain. PAK kinases are implicated in theregulation of a number of cellular processes, including cytoskeletonrearrangement, apoptosis and the MAP kinase signaling pathway. |
| Source : |
Insect cells |
| Species : |
Human |
| Form : |
Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol. |
| Molecular Weight : |
79.9 kDa |
| Storage : |
Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
| OfficialSymbol : |
PAK6 |
| Gene Name : |
PAK6 p21 protein (Cdc42/Rac)-activatedkinase 6 [ Homo sapiens ] |
| Synonyms : |
PAK6; p21 protein(Cdc42/Rac)-activated kinase 6; PAK5; p21-activated kinase 6;p21(CDKN1A)-activated kinase 6; p21-activated protein kinase 6; EC 2.7.11.1;PAK-5; PAK-6; Serine/threonine-protein kinase PAK 6 |
| Gene ID : |
56924 |
| mRNA Refseq : |
NM_020168 |
| Protein Refseq : |
NP_064553 |
| MIM : |
608110 |
| UniProt ID : |
Q9NQU5 |
| Chromosome Location : |
15q14 |
| Pathway : |
Activation of Rac;Androgen Receptor Signaling Pathway; Axon guidance; CDC42 signaling events;Developmental Biology; ErbB signaling pathway; Focal adhesion;Integrin-mediated cell adhesion; Regulation of actin cytoskeleton; Renal cellcarcinoma; Signaling by Robo receptor; T cell receptor signaling pathway |
| Function : |
ATP binding;nucleotide binding; protein serine/threonine kinase activity |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
