||Recombinant humanfull length PAK6 is a serine/threonine kinase expressed in the testis andprostate. Itassociates with both the estrogen and androgen receptors. No special measureswere taken to activate this kinase. Itsmolecular weight is 79900 Dalton.
||Serine/threonine-proteinkinase PAK6 is an enzyme that in humans is encoded by the PAK6 gene. Thisgene encodes a protein that shares a high degree of sequence similarity withp21-activated kinase (PAK) family members. The proteins of this family areRac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by ahighly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domainand a carboxyl-terminal kinase domain. PAK kinases are implicated in theregulation of a number of cellular processes, including cytoskeletonrearrangement, apoptosis and the MAP kinase signaling pathway.
||Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
||Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.