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Recombinant Mouse Plasminogen Activator, Urokinase Receptor, His-tagged

Cat. No.: Plaur-1299M
Product Overview: Recombinant mousePlaur was expressed in insect cells.
Description: Plaur isrequired for the recruitment of neutrophils in response toinfection. uPA induces its own expression in lungepithelial cells, which involves its interaction with cell surface Plaur.Regulation ofPlaurexpression is therefore crucial for uPA-mediated signaling in infectiousacute lunginjury(ALI). Contains a 6X-Histidine tag at N terminus for purification.
Source: Insect cells
Species: mouse
Form: Frozen Liquid in 0.1M Tris-HCl pH 7.0 + 0.15 M NaCl.
Volume: 0.05 mL
Concentration: 2.0 mg/mL
Biological Activity: Demonstratespreferential binding to Mouse uPA over Human uPA coated on an ELISA plate.
Storage: Store at -70°C. Avoidrepeated freeze-thaw cycles.
OfficialSymbol: Plaur
Gene Name: Plaur plasminogen activator,urokinase receptor [ Mus musculus ]
Synonyms: Plaur; plasminogenactivator, urokinase receptor; Cd87; uPAR; u-PAR; urokinase plasminogenactivator surface receptor; urokinase plasminogen activator receptor; urokinase-typeplasminogen activator receptor
Gene ID: 18793
mRNA Refseq: NM_011113
Protein Refseq: NP_035243
UniProt ID: P35456
Chromosome Location: 7 A3
Pathway: Attachment of GPIanchor to uPAR; Complement and Coagulation Cascades; Complement andcoagulation cascades; Complement and coagulation cascades; Dissolution ofFibrin Clot; Hemostasis; Metabolism of proteins; Post-translationalmodification: synthesis of GPI-anchored proteins; Post-translational proteinmodification
Function: U-plasminogenactivator receptor activity; enzyme binding; kinase activity; proteinbinding; receptor activity

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