Native Rat Natriuretic Peptide B


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Native Rat Natriuretic Peptide B

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Cat.No. : Nppb-5459R
Product Overview : Nppb is a 32 aapeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes in the ventricles. A high concentration of thisprotein in the bloodstream is indicative of heart failure.
Description : Native Rat Nppb, also known as BrainNatriuretic Peptide-32 (BNP32) is a member of the natriuretic peptide familyand is a secreted protein which functions as a cardiac hormone. The proteinundergoes two cleavage events, one within the cell and a second aftersecretion into the blood. The protein"s biological actions includenatriuresis, diuresis, vasorelaxation, inhibition of renin and aldosteronesecretion, and a key role in cardiovascular homeostasis.
Source : Rat
Species : Rat
Form : TrifluoroacetateSalt.
AA Sequence : Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys-Phe-Gly-Gln-Lys-lle-Asp-Arg-lle-Gly -Ala-Val-Ser-Arg-Leu-Gly-Cys-Asp-Gly-Leu-Arg-Leu-Phe
Purity : ≥99%
Storage : Store at -20°C.
Gene Name : Nppb natriuretic peptide B [ Rattus norvegicus ]
Official Symbol : Nppb
Synonyms : NPPB; natriuretic peptide B; natriuretic peptides B; iso-ANP; Brain natriuretic factor; brain natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor B; natriuretic peptide precursor type B; BNP; Bnf;
Gene ID : 25105
mRNA Refseq : NM_031545
Protein Refseq : NP_113733
Chromosome Location : 5q36
Function : hormone activity; peptide hormone receptor binding; receptor binding;

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