"IL6R" Related Products

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Recombinant Human Interleukin 6 Receptor, His-tagged

Cat. No.: IL6R-1241H
Product Overview: Recombinant humanIL6R is a single, non-glycosylated polypeptide chain containing 338 aminoacids (aa 20-357) corresponding to the mature IL6R protein with an aminoterminal hexahistidine tag.
Description: The IL6R complex is composed of two membrane glycoproteins: thelow affinity receptor and the signaltransducing component. The soluble formof IL6R is found in the urine of healthy adult humans and the serum of HIVpositive individuals, as well as in the cell culture supernatants ofstimulated PBMC's. This soluble form of IL6R results from either proteolyticcleavage from the membrane, or an isoform derived splice variant.
Source: E. coli
Species: Human
Form: Liquid in 20 mM TrisHCl pH 8 + 50% glycerol.
MolecularWeight: 42.25 kDa
Purity: > 95% by SDS-PAGEand HPLC analyses
Endotoxin Level: <0.1 ng/µg of IL6R
Storage: Store at 2-4°C ifentire vial will be used within 2-4 weeks. Store, frozen at -20°C for longerperiods of time. Avoid repeated freeze-thaw cycles.
OfficialSymbol: IL6R
Gene Name: IL6R interleukin 6 receptor [ Homosapiens ]
Synonyms: IL6R; interleukin 6 receptor; CD126; IL-6R-1; IL6R-alpha; IL-6R-alpha; IL6RA;MGC104991; OTTHUMP00000034320; gp80; CD126 antigen; IL-6R 1; Interleukin-6receptor alpha chain precursor; B cell stimulatory factor-2; Membraneglycoprotein 80; interleukin 6 receptor; interleukin 6 receptor alpha subunit
Gene ID: 3570
mRNA Refseq: NM_000565
Protein Refseq: NP_000556
MIM: 147880
UniProt ID: P08887
Chromosome Location: 1q21
Pathway: Cytokine-cytokine receptorinteraction; Hematopoietic cell lineage; Jak-STAT signaling pathway
Function: ciliary neurotrophic factorbinding; ciliary neurotrophic factor receptor activity;enzyme binding;interleukin-6 receptor activity; protein homodimerization activity; receptorbinding

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