Recombinant Human TRAF-Interacting Protein With Forkhead-Associated Domain, His-tagged
Cat.No. : | TIFA-5552H |
Product Overview : | Recombinant humanTIFA protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TIFA-5552H |
Description : | TIFA, also known asTRAF-interacting protein with FHA domain-containing protein A, is an adapterprotein which mediates the IRAK1 and TRAF6 interaction following IL-1stimulation, resulting in the downstream activation of NF-kappa-B and AP-1pathways. This protein induces the oligomerization and polyubiquitination ofTRAF6, which leads to the activation of TAK1 and IKK through aproteasome-independent mechanism. |
Source : | E. coli |
Species : | Human |
Form : | Liquid. 20mMTris-HCl buffer (pH8.0) containing 20% glycerol 1mM DTT. |
Molecular Weight : | 24.0 kDa (208aa)confirmed by MALDI-TOF. |
Purity : | > 90% by SDS - PAGE. |
Concentration : | 0.5 mg/ml(determined by Bradford assay). |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSHMTSFED ADTEETVTCL QMTVYHPGQL QCGIFQSISF NREKLPSSEV VKFGRNSNICHYTFQDKQVS RVQFSLQLFK KFNSSVLSFE IKNMSKKTNL IVDSRELGYL NKMDLPYRCM VRFGEYQFLMEKEDGESLEF FETQFILSPR SLLQENNWPP HRPIPEYGTY SLCSSQSSSP TEMDENES |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
OfficialSymbol : | TIFA |
Pathways : | TNF-alpha/NF-kBSignaling Pathway |
Gene Name : | TIFA TRAF-interacting proteinwith forkhead-associated domain [ Homo sapiens ] |
Synonyms : | TIFA;TRAF-interacting protein with forkhead-associated domain; T2BP; T6BP; TIFAA;TRAF-interacting protein with FHA domain-containing protein A; TRAF2 bindingprotein; TRAF2-binding protein; TRAF6 binding protein; putativeMAPK-activating protein PM14; putative NF-kappa-B-activating protein 20; TRAF-interactingprotein with a forkhead-associated domain |
Gene ID : | 92610 |
mRNA Refseq : | NM_052864 |
Protein Refseq : | NP_443096 |
MIM : | 609028 |
UniProt ID : | Q96CG3 |
Chromosome Location : | 4q25 |
Function : | protein binding |
Products Types
◆ Recombinant Protein | ||
TIFA-4528R | Recombinant Rhesus Macaque TIFA Protein, His (Fc)-Avi-tagged | +Inquiry |
TIFA-5720R | Recombinant Rat TIFA Protein, His (Fc)-Avi-tagged | +Inquiry |
TIFA-4714R | Recombinant Rhesus monkey TIFA Protein, His-tagged | +Inquiry |
TIFA-6063R | Recombinant Rat TIFA Protein | +Inquiry |
TIFA-3231H | Recombinant Human TIFA, GST-tagged | +Inquiry |
◆ Lysates | ||
TIFA-1078HCL | Recombinant Human TIFA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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