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Active Recombinant Mouse Intercellular Adhesion Molecule 5, Telencephalin, Fc-tagged

Cat.No. : Icam5-5641M
Product Overview : RecombinantMouse Icam5 protein was expressed in Murine myeloma cell line with the Fcpart of Human IgG1 Pro100-Lys330 (C-terminus) and Mouse Icam5 Leu31-Arg828(Pro47Arg) (N-terminus).
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Cat. No. : Icam5-5641M
Description : Icam5 isan integral membrane glycoprotein expressed in neurons of mammalian telencephalons.Icam5 is a member of the immunoglobulin superfamily and shares 38-55% aminoacid homology with other ICAMs. Structurally, Icam5 contains nine Ig domainsthat included 15 N-glycosylation sites, a single transmembrane region, and C-terminalcytoplasmic tail. As with other members of the ICAM family, Icam5 has beenshown to be involved in cellular adhesion.
Source : Mammalian cells
Form : Lyophilizedfrom a 0.2 um filtered solution in Tris-Citrate and NaCl.
N-terminalSequence : Leu31
MolecularWeight : 112 kDa (monomer)
Activity : Measuredby the ability of the immobilized protein to support the adhesion ofPMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemiacells. When 5x104 cells/well are added to rh Icam5/FcChimera coated plates (25 μg/mL with 100 μL/well), > 25% cells will adhereafter 1 hour incubation at 37°C.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 166 kDa,reducing conditions.
Purity : >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 400 μg/mLin sterile PBS
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : Icam5 intercellular adhesionmolecule 5, telencephalin [ Mus musculus ]
Official Symbol : Icam5
Synonyms : Icam5; intercellularadhesion molecule 5, telencephalin; TLN;CD50; Tlcn; Icam3; ICAM-3; intercellular adhesion molecule 5; ICAM-5;telencephalin; intercellular adhesion molecule 3
Gene ID : 15898
mRNA Refseq : NM_008319
Protein Refseq : NP_032345
UniProt ID : Q60625
Chromosome Location : 9
Function : protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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