Active Recombinant Mouse Insulin-Like Growth Factor Binding Protein-Like 1, His-tagged

• Cat.No.: Igfbpl1-5646M
• Product Overview: RecombinantMouse Igfbpl1 protein was expressed in Murine myeloma cellline. Leu18-Leu270,with a C-terminal 10-His tag.

Specification

• Cat. No.: Igfbpl1-5646M
• Description: Igfbpl1is a 38 kDa secreted member of the IGFBP superfamily of proteins. IGFBP superfamilymembers are cysteine-rich proteins with conserved cysteine residues, whichare clustered in the amino-and carboxy-terminal thirds of the molecule.IGFBPs modulate the biological activities of IGF proteins. Igfbpl1 containsan N-terminal IGFBP motif, a Kazal-type serine protease inhibitor region, anda C-terminal Ig-like domain. Mature mouse Igfbpl1 shares 76% and 96% aminoacid (aa) sequence identity with human and rat Igfbpl1, respectively.
• Source: Mammalian cells
• Form: Lyophilized from a0.2 um filtered solution in PBS.
• N-terminalSequence: Leu18
• MolecularWeight: 28.2 kDa
• Activity: Measuredby its ability to inhibit proliferation of HeLa human cervical epithelial carcinomacells. The ED50 for this effect is typically 2-8 μg/mL.
• Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
• SDS-PAGE: 36 kDa,reducing conditions.
• Purity: >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: 100 μg/mLin sterile PBS
• Storage: Use a manual defrost freezer and avoid repeated freeze-thawcycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.

Gene Information

• Gene Name: Igfbpl1 insulin-like growthfactor binding protein-like 1 [ Mus musculus ]
• Official Symbol: Igfbpl1
• Synonyms: Igfbpl1;insulin-like growth factor binding protein-like 1; IGFBPL;2810011G06Rik; 2810453O06Rik; insulin-like growth factor-binding protein-like1; IGFBP-rP4; IGFBP-like protein; IGFBP-related protein 10; insulin-likegrowth factor-binding-related protein 4
• Gene ID: 75426
• mRNA Refseq: NM_018741
• Protein Refseq: NP_061211
• UniProt ID: Q80W15
• Chromosome Location: 4
• Function: insulin-like growthfactor binding