"NLGN2" Related Products

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Recombinant Human Neuroligin 2, His-tagged

Cat. No.: NLGN2-5692H
Product Overview: Recombinant Human NLGN2protein was expressed in Murine myeloma cell line with a C-terminal 6-Histag. Gln15-Ser660.
Description: NLGN2 is one of severaltype I transmembrane Neuroligins that are expressed on neuronal postsynapticdensities. Neuroligins play an important role in synaptic development andfunction. Mature human NLGN2 is a 105 kDa protein that consists of a 663amino acid extracellular domain with a catalytically inactive cholinesterase-likedomain, a 21 aa transmembrane segment, and a 137 aa cytoplasmic tail. Withinthe ECD, human NLGN2 shares 98% aa sequence identity with mouse and ratNLGN2.
Source: Murine myeloma cellline, NS0-derived.
Form: Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence: Gln15 predicted
Molecular Weight: 72 kDa
Activity: Measuredby its binding ability in a functional ELISA. When recombinant human NLGN2 is immobilized at 1.5 μg/mL, recombinant human Neurexin1β Fc Chimera binds with an apparent KD < 10 nM.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE: 85-95kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: 400μg/mL in PBS
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterile conditionsafter reconstitution.
Gene Name: NLGN2 neuroligin 2 [ Homosapiens ]
Official Symbol: NLGN2
Synonyms: NLGN2; neuroligin 2;KIAA1366; neuroligin-2; OTTHUMP00000135277; EC 3.1.1; EC 3.1.1.1
Gene ID: 57555
mRNA Refseq: NM_020795
Protein Refseq: NP_065846
MIM: 606479
UniProt ID: Q8NFZ4
Chromosome Location: 17p13.2
Pathway: Cell adhesion molecules (CAMs)
Function: NOT carboxylesterase activity; cell adhesionmolecule binding; neurexin family protein binding; receptor activity

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